The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
I purchased Ananda professional full spectrum Extract 600 20/mg/ml CBD oil. I started with .5ml dose the first night right before bedtime. I did not sleep well. I tried the same dose the following evening, and again, poor sleep. I tried it for two more nights and had the same results. I’m very sensitive to steroids and will only use them as a last resort, but the way I felt after taking the CBD oil, reminded me of how poor my sleep is on steroids. Or how vitamin B12 can affect me if I take it too late in the day. I have a lot of inflammation and pain and hoped the CBD oil would help. I am quite surprised at my reaction to it. Anyone else have trouble sleeping when taking it?
We take an extra step. Using advanced chromatography, Calm Hemp Oil is free of THC, while retaining the full spectrum of cannabinoids, terpenes and flavonoids that create an entourage effect and may support full-body health. Calm hemp oil comes from premium non-GMO strains of hemp, organically grown in Colorado, USA and is 100% natural, with a refreshing mint taste.

This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.

Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”
Another field in which CBD is creating a buzz is in the area of mood disorders like anxiety and depression. Both conditions have been treated with a variety of medications, courtesy of Big Pharma, that have had varying levels of success. Again, the long list of side effects can be off-putting to someone who just wants to get through the day without the sweaty tension of anxiety or the gray haze of depression.

A high quality brand of CBD will always provide third-party lab results to their consumers. Some laboratories finds favorable results, while some products fail these tests. These independent labs exist to ensure that CBD oil is everything it claims to be, with a high level of CBD, low THC, and lacking in impurities that can be harmful to consumers.
Mimi says the effective oils are made from the marijuana plant, not hemp. Why are you rating only hemp oils? Are hemp oils the only oils that do not have any THC? The other question that arises is the difference between ml and mg in measuring the strength of these oils. They are quoted as ml, but there is the question of the “density” limit of 95mg? Very confusing.

I am very pleased with the quality and the price of the high potency cbd. I have had my medical cannabis card for years and really became trusted with the high cost of my natural medicine, because the high costs and low cbd dosages found in the dispensaries. Now I can purchase high quality and high potency pure cbd oil at a great price without the worries of traveling with banned substances. Works better than xanax or antidepressants and no pharmaceutical side effects! I always take with my morning coffee and for pain and stress as needed. The only concern I have is with the shipping method as I would really benefit from USPS priority shipping instead of waiting for the long cross country ups ground, as the ups 3 day is very expensive. Besides the shipping options, I give this an A+! Thank you.


Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.
In the United States, over three million people suffer from epilepsy – 470,000 of those people are children. Epilepsy is a disorder of the brain that causes seizures – of which there are over thirty different kinds, ranging from mild and infrequent to life-threatening. Not surprisingly, people with epilepsy face significant challenges – from the cost of healthcare to work limitations and social isolation.
So, the next question is typically:  DO I NEED ALL THESE OTHER CANNABINOIDS TO HELP MY CANCER (or epilepsy, diabetes, etc)?  The answer is “maybe”.  Some people find great results from cannabidiol or CBD alone.  But, more people typically report better results when taking a full spectrum of cannabinoids (sometimes this includes THC, but often times, not).  So, if you’re new to CBD and not sure what direction to go, these reports from people would generally indicate its best to try a full spectrum blend to give you the greatest chance of success.  While having an extract that includes specifically the cannabinoid THC could also increase your chance for success, you have to ask yourself if you want to be ‘high’ all day when taking CBD.  And, you have to consider whether CBD extracted from marijuana is legal where you are.  Because of these two questions, CBD as part of a full spectrum of cannabinoid extracted from hemp, is often times the desired choice.

The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.

I use plus CBD brand for my patients and myself.It’s a fantastic company with a great reliable product. They have the biggest share of retail outlets in the country so they have to be priced right and labeled properly. They also have GRAS rating. That means generally regarded as safe. They are the only CBD company to do the research and spend the money to get that rating. I love the gummies.


This is my experience with taking CBD 3000mg for the last 6 months. My blood pressure has gone down, I am able to sleep better, the eczema on my hand has disappeared (using a drop or two twice a day on the area). Sort of did an assessment of my body/joints. Everything feels different in a good way. Joints seem to move smoother than before taking CBD. All is great here. Thanks, Lazarus Naturals for such great reasonably priced products.
I just wanted to say thank you. My 19 year old daughter has been suffering from chronic back pain since age 13. She has been to multiple doctors and chiropractors and has had MRIs and x-rays. Has been on multiple medications for pain and nothing was working. I decided to try purchase your high potency CBD oil as a last resort and to both of our astonishment for the first time she hasn’t had pain during the 2 weeks she has been taking it. I will be purchasing more of your product. Thank you so much.
I’ve been taking the high potency tincture for a week and can’t believe how good it is. I tried several products purchased from my local CBD store and got no effect from them even when taking higher doses. I bought the high potency sample pack here and it fantastic. I just wish they had a vape product without PG/VG for quicker relief but until they do I’ll continue to purchase this product.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.
Thousands of people have learned about the healing benefits of CBD, resulting in unprecedented interest in this supplement. People are using CBD oil to ease their chronic pain, and relieve symptoms of conditions ranging from arthritis to depression. Unlike its close cousin, psychoactive cannabis (‘marijuana’), CBD oil won’t make you feel high — but many users report significant relief of their symptoms. Even the World Health Organization declared CBD oil safe and worthy of deeper research.

These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”

It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.
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