We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.
Tetrahydrocannabinol, or THC, is one of the cannabinoids present in both marijuana and agricultural hemp, and it is the substance responsible for giving a psychoactive effect on the body. It is what gives a user a “high.” The reason why hemp is used over marijuana when creating CBD oil is because of the former’s innate low levels of THC over CBD, making it perfect for CBD oil processing.
As the term suggests, full spectrum CBD comes with all the of the cannabinoids present in the plant. In hemp oil, this includes a long list of cannabis compounds, such as Cannabinol (CBN), Cannabicyclol (CBL), Tetrahydrocannabivarin (THCV) and Cannabichromevarinic Acid (CBCVA). It is crucial to point out that small amounts of THC can also be found in hemp. The government regulates concentration levels at 0.3 percent (dry weight) for “industrial hemp” products, resulting in very limited cerebral stimulation.
Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.
Cannabigerol is known as the stem cell cannabinoid for its role as a precursor to other cannabinoids found in hemp and marijuana. Previously overlooked as a significant cannabinoid, the role of CBG is becoming better understood, and companies like Medical Marijuana, Inc.’s AXIM® Biotechnologies are starting to research its potential. Because most CBG is transformed into other cannabinoids like CBD or THC by the cannabis plant, natural CBG levels are low in most processed cannabis plants.
So a full spectrum decarb got higher points than isolate (“decarb” just refers to the process of decarboxylation which turns raw CBD into activated CBD). We also gave more points to companies with a “broad spectrum” tincture. Broad spectrum CBD oil includes a range of other cannabinoids, but minus the THC – which is generally what people using isolates are trying to avoid.
Seeing how well this product worked, I went on to sample other brands and various products of CBD and Hemp Extracts- This resulted as a waste of time and money because every top brand I’d read about online was either complete garbage (one brand starting with the letter E ending with L made me violently ill and I can’t even uncap the bottle without being made to feel sick) OR there was no discernible difference between those products and Lazarus. Keeping these facts in mind, there is absolutely without a doubt- no other product of CBD oil that can compete with these guys(Lazarus Naturals).