The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:

CBD Oil Full Spectrum


I had bilateral partial knee replacements 3-5 years ago then scar tissue removal in my right knee. I have always had some pain and stiffness in the right knee since my last surgery, probable due to more scar tissue. I am not ready for more surgery yet. I am mostly on my feet for 12 hours at work. About a year ago the pain in my knee got so intense I was only able to sleep for only several hours a night even with an ice bag on my knee. I started shopping for CBD online. Tried several brands before finding Lazarus which is much better than the others at a better price. My pain is 90-95 % gone and I sleep like baby all night. Helps with anxiety. Thank you! Please don’t stop making a great product.

These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”
And now, onto the thorny issue of legality. The simple answer to the question is yes – if it is extracted from hemp. The 2014 Farm Bill established guidelines for growing hemp in the U.S. legally. This so-called  “industrial hemp” refers to both hemp and hemp products which come from cannabis plants with less than 0.3 percent THC and are grown by a state-licensed farmer.

There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
As the term suggests, full spectrum CBD comes with all the of the cannabinoids present in the plant. In hemp oil, this includes a long list of cannabis compounds, such as Cannabinol (CBN), Cannabicyclol (CBL), Tetrahydrocannabivarin (THCV) and Cannabichromevarinic Acid (CBCVA). It is crucial to point out that small amounts of THC can also be found in hemp. The government regulates concentration levels at 0.3 percent (dry weight) for “industrial hemp” products, resulting in very limited cerebral stimulation.
These drops are worth every penny! I first tried the 3,000 mg. Then bumped it up to 6000mg. I use about 1-1.5ml per day. I was hit head-on by a drunk when I was 19 in 1995. Coma 6 weeks hospital 6 months. This makes my life so much easier to live! Thank you Lazarus naturals for making such an awesome product!! And for making it so affordable! These products are worth their weight in gold!
Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.

High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.

Disclaimer: The Federal Food, Drug and Cosmetic Act requires this disclaimer. We collected this information from various sources for the convenience of our customers. The statements made regarding these products were not evaluated by the Food and Drug Administration. The efficacy of these products is not confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure, or prevent any disease. The information presented here is not meant as a substitute for information from health care practitioners. It is also not meant as an alternative to information from health care practitioners. Before using any product, you should consult your doctor and ask about the risk of interactions or complications.

We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
Seeing how well this product worked, I went on to sample other brands and various products of CBD and Hemp Extracts- This resulted as a waste of time and money because every top brand I’d read about online was either complete garbage (one brand starting with the letter E ending with L made me violently ill and I can’t even uncap the bottle without being made to feel sick) OR there was no discernible difference between those products and Lazarus. Keeping these facts in mind, there is absolutely without a doubt- no other product of CBD oil that can compete with these guys(Lazarus Naturals).
Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as  a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).

In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.

Some companies, especially those who sell their products at a ridiculously low price, may use cheap methods when extracting CBD oil. This requires toxic solvents that are dangerous to our health such as propane, hexane, pentane and butane. Two of these are commonly used in gas stoves and ranges, such as propane and butane, and all of them are hydrocarbon gases found in petroleum.

Thank you for a great product. I have been in constant pain for almost 17 years. It has helped relax my muscles so much better than what I can get prescribed by my doctors here. I am using Tylenol intermittently with it to space out the dosage. I haven’t noticed any side effects from it . This is my first time trying this and I am well pleased. Thank you again for this, it is a game changer for me.
Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
I have fibromyalgia and piriformious syndrome (severe hip/leg pain) and for the past six months have been dealing with extreme pain and insomnia. Having exhausted all tricks, remedies, doctors, and medications without relief I decided to try Cbd oil. After only two days I have slept like a baby, had hours of continuous deep sleep, sleep app confirmed this. The Hip/leg pain is dulled, but dulled enough that I can do therapy stretches without screaming or crying. The nerve pain from fibro feels like it is asleep! It is the most amazing thing not to feel every nerve in your body after three years of constant pain. The cbd oil does give me a slight tummy ache after taking it but goes away in about an hour. And I do mean slight ache. So far no side effects or interactions. ( Will up date if do)
Although low, the original amount of THC present in hemp may still cause a certain level of psychoactive effects when processed incorrectly. Remember, CBD oil is made from the extracts of hundreds, even thousands, of hemp plants, therefore, no matter how small a percentage of THC there is in hemp, it may still have a high concentration on CBD oils that have been processed poorly, especially since the equipment needed to properly process CBD oil from hemp can be costly.

So a full spectrum decarb got higher points than isolate (“decarb” just refers to the process of decarboxylation which turns raw CBD into activated CBD). We also gave more points to companies with a “broad spectrum” tincture. Broad spectrum CBD oil includes a range of other cannabinoids, but minus the THC – which is generally what people using isolates are trying to avoid.


I love this company and their amazing products! I have tried different CBD oils from 6 different companies, none of them came close to Lazarus Naturals. It was the first oil I tried and probably will be the one I continue to use for a very long time. This tincture helped me immensely! It gave me energy but also calmed my mind down as well. Another thing, their customer service is fantastic! I paid for express 2-day shipping on one of my previous orders but there was a miscommunication and it ended up being shipped standard and took a few more days then I expected. So I emailed them and they emailed me back the same day and refunded me the shipping costs. Overall, excellent high-quality products and amazing company! Thank you, guys!
Seeing how well this product worked, I went on to sample other brands and various products of CBD and Hemp Extracts- This resulted as a waste of time and money because every top brand I’d read about online was either complete garbage (one brand starting with the letter E ending with L made me violently ill and I can’t even uncap the bottle without being made to feel sick) OR there was no discernible difference between those products and Lazarus. Keeping these facts in mind, there is absolutely without a doubt- no other product of CBD oil that can compete with these guys(Lazarus Naturals).

In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.


Our hemp extracts are rich in many cannabinoids, beyond cannabidiol (CBD), and contain a host of terpenes as well. Cannabinoids present in our extracts include, but are not limited to, testable amounts of CBD, CBG, and CBC. Present terpenes in our extracts include, but are not limited to, testable amounts of alpha-Pinene, beta-Myrcene, beta-Pinene, d-Limonene, Linalool, beta-Caryophyllene, and alpha-Humulene. Each of these cannabinoids and terpenes enhance the overall therapeutic effect of CBD and this is why they are very important to the quality of our products. The presence of these accompanying cannabinoids and terpenes, in addition to CBD, is referred to as “Full Spectrum.”
It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.
Full Spectrum generally refers to CBD oil products that not only contain CBD,but also contain some terpenes and other cannabinoids such as CBG, CBN and even some THC. Usually these will be in ratios that were naturally occurring and extracted from the plant and specific strain. But they are also occasionally added back into products as an isolated form to raise the potency of the product. For those that get drug tested, Full Spectrum is something to be cautious about. The THC found in full spectrum hemp products is minimal (less than 0.3%), but can still trigger positive drug tests.
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).

Another quality of a good CBD oil is that it is manufactured using the whole plant. CBD Isolates are becoming increasingly popular, but in reality, it is a cheaper material than whole plant extracts.  Using the whole plant, rather than using only one part, ensures that the oil contains not just CBD, but also the full range of primary and secondary constituents of the hemp plant. These include terpenes, flavonoids, and other cannabinoids that are generally believed to work synergistically with CBD, making the benefits exponentially higher than CBD alone.
Full Spectrum generally refers to CBD oil products that not only contain CBD,but also contain some terpenes and other cannabinoids such as CBG, CBN and even some THC. Usually these will be in ratios that were naturally occurring and extracted from the plant and specific strain. But they are also occasionally added back into products as an isolated form to raise the potency of the product. For those that get drug tested, Full Spectrum is something to be cautious about. The THC found in full spectrum hemp products is minimal (less than 0.3%), but can still trigger positive drug tests.
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