Unfortunately, it’s not always easy for consumers to determine which CBD brands and product claims’ are trustworthy. With the growth in popularity of CBD oil, new brands and merchants are coming out every day with promises to offer you the best, high-quality supplement. However, there are few regulations, if any, to help monitor and regulate these claims.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
You may have read or heard in the news all the reports of people wanting to take CBD Oil for many ailments, some of which are cancer, epilepsy, chronic pain, TMJ, anxiety and diabetes.  And, many people are reporting some pretty fantastic improvements to their conditions after taking these oils.   The first thing most people want to know is: IS THERE ANY DIFFERENCE BETWEEN CANNABIDIOL FROM HEMP AND CANNABIDIOL FROM MARIJUANA?  And, the short answer is “no”; molecularly, CBD is CBD.  But, there are generally some differences in the CBD Extracts.  Let me explain this a bit further.
When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
For our review of the best CBD topicals available online, we focused only on companies which make third-party, independent lab results available to consumers. Lab results are available online, included in the order, or on request. It’s vitally important that consumers know exactly what products they’re consuming: how strong it is, and whether it has any impurities. We also focused on brands with fast, friendly customer service and easy to use websites.
High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.
Another quality of a good CBD oil is that it is manufactured using the whole plant. CBD Isolates are becoming increasingly popular, but in reality, it is a cheaper material than whole plant extracts.  Using the whole plant, rather than using only one part, ensures that the oil contains not just CBD, but also the full range of primary and secondary constituents of the hemp plant. These include terpenes, flavonoids, and other cannabinoids that are generally believed to work synergistically with CBD, making the benefits exponentially higher than CBD alone.

Hemp CBD Oil THC Free


You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).
Based on the comparison above, full spectrum hemp oil is more effective than CBD isolate, making it highly recommended for patients interested in holistic approaches to medicinal cannabis treatments. Hemp oil is an extremely potent source of CBD (responsible for a large bulk of the oil’s cannabinoid profile). To fully reap CBD oil benefits, one should explore the different mediums of the compound available on the market today.
Similarly, transparency is one of our top concerns when it comes to selecting the best CBD oil tinctures. Every product below is clearly labeled, so you can easily understand how much CBD oil / full spectrum hemp extract is in each bottle. You can also easily find the complete ingredients on the bottle, packaging or the company’s website. These brands are also open about where they source their hemp.

Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity. But THC metabolites are stored in the fat cells of your body, building up over time. If you ever need to take a drug test, this could create an issue for you.

Marijuana & hemp are both cannabis sativa (and some marijuana is cannabis indica). But “industrial hemp” (the only source of CBD lawful in all 50 states, thanks to the Federal Farm Bill’s exemption of it from the Controlled Substances Act) CBD extract products are lawful in all 50 states, can be sold on the open market at any store (not just a licensed dispensary) or online to anyone over 18–regardless of the customer’s or mfr’s state’s medical or recreational weed laws.
THC is the plant compound that makes a person feel ‘high’.  It is naturally found in much higher quantities in marijuana, and in virtually non-existent quantities in hemp. So, when taking a full spectrum cannabinoid extract from hemp, the THC level is so low that you do not feel ‘high’ or groggy.  But, when taking CBD extracted from marijuana, even the “low CBD” strains typically have enough THC to cause someone to feel slightly ‘high’ or at least sleepy or groggy.  And, if its NOT a low CBD strain of marijuana, then watch out, you will most likely experience a pretty significant ‘high’.
The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.
Cannabigerol is known as the stem cell cannabinoid for its role as a precursor to other cannabinoids found in hemp and marijuana. Previously overlooked as a significant cannabinoid, the role of CBG is becoming better understood, and companies like Medical Marijuana, Inc.’s AXIM® Biotechnologies are starting to research its potential. Because most CBG is transformed into other cannabinoids like CBD or THC by the cannabis plant, natural CBG levels are low in most processed cannabis plants.
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:

CBD Oil Full Spectrum

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