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The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
Being a hyperaccumulator also has drawbacks: If a hemp plant that is used in production of CBD oil was cultivated in a land that is rich in heavy metals such as mercury and lead, the resulting oils will also reflect the amount of heavy metals absorbed by the plant, making it unsafe for humans to consume, especially children or others who are extremely vulnerable to toxins.