When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.
Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger
Based on the comparison above, full spectrum hemp oil is more effective than CBD isolate, making it highly recommended for patients interested in holistic approaches to medicinal cannabis treatments. Hemp oil is an extremely potent source of CBD (responsible for a large bulk of the oil’s cannabinoid profile). To fully reap CBD oil benefits, one should explore the different mediums of the compound available on the market today.
All I am seeing on this site is this brand is fantastic and that brand is fantastic! I don’t think I could trust any of these with the exception of one. I believe the only way to actually get good quality CBD is from a state licensed dispensary. Everyone else just wants to make a quick buck by jumping on the hype that it is now legal in all 50 states! I have cancer and herniated discs and fibromyalgia, asthma, PTSD, CFS severe anxiety, etc and will be starting radiation shortly. My pain right now is off the charts. I am afraid of most medications and pretty much will not take too many things. So when I get the CBD oil I will do it in front of a doctor to make sure of allergies. It will have to be of high quality and something that will not get me high! The fear of taking something from just any online distributor doesn’t ensure quality. If anyone out there can tell me with the most positive knowledge that a product is what it is then you can let me know. Any recommendations?
Let’s not forget about terepenes and flavonoids too. While not cannabinoids from hemp, they are compounds found in hemp and other plants. Terpenes are fragrant oils that bind to receptors in the human body and carry a variety of health benefits.* Flavonoids are a group of phytonutrients that serve as cell messengers with their own health-promoting benefits,  
The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.
Hi Stephen, this is something we are currently working on. The difficulty with full spectrum products is that the terpenes and plant matter which people attribute benefits to, also bring with them the essential flavors of hemp. We have designed two new full spectrum flavors (french vanilla mocha and chocolate mint) which mask the hemp flavor, but it will be a few months until we have ramped up the production necessary to support these products.
While there is much debate on which form is better, this 2015 study (http://file.scirp.org/pdf/PP_2015021016351567.pdf) leans in favor of Full Spectrum products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) instead of Full Spectrum.
Yes! In addition to the rigorous quality assurance testing that Calm Premium Hemp Oil undergoes before it goes in the bottle, it is also sent out for independent analysis. This testing is conducted at ProVerde Labs, and shows that Calm Premium Hemp Oil is a full spectrum hemp oil rich in cannabinoids and terpenes with zero THC. You can view the lab certificate online > click here

On a molecular level, all classes of cannabinoid are derived from the cannabinoid cannabigerol (CBG). Cannabinoids are changed from their original acid forms by decarboxylation through heat, light, or alkaline conditions, allowing them to interact fully with the endocannabinoid system. Learn more about all the cannabinoids found in our full spectrum hemp oil below:
This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.

Yes! In addition to the rigorous quality assurance testing that Calm Premium Hemp Oil undergoes before it goes in the bottle, it is also sent out for independent analysis. This testing is conducted at ProVerde Labs, and shows that Calm Premium Hemp Oil is a full spectrum hemp oil rich in cannabinoids and terpenes with zero THC. You can view the lab certificate online > click here


Thank you for a great product. I have been in constant pain for almost 17 years. It has helped relax my muscles so much better than what I can get prescribed by my doctors here. I am using Tylenol intermittently with it to space out the dosage. I haven’t noticed any side effects from it . This is my first time trying this and I am well pleased. Thank you again for this, it is a game changer for me.
So a full spectrum decarb got higher points than isolate (“decarb” just refers to the process of decarboxylation which turns raw CBD into activated CBD). We also gave more points to companies with a “broad spectrum” tincture. Broad spectrum CBD oil includes a range of other cannabinoids, but minus the THC – which is generally what people using isolates are trying to avoid.
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My bigger question is what about analytics ? So many bad lab’s out there in Cannabis and Hemp. Did they test for Pesticides ? Mycotoxins ? Heavy Metals (Hemp is great at dragging up heavy metals from the soil as well as from nutrient solutions, herbicides, etc..). The testing piece is critical and that a lab performs random testing to ensure that the final products on the shelf actually contain what’s on the label. Even good test results mean nothing if the product is cut after the testing.
These drops are worth every penny! I first tried the 3,000 mg. Then bumped it up to 6000mg. I use about 1-1.5ml per day. I was hit head-on by a drunk when I was 19 in 1995. Coma 6 weeks hospital 6 months. This makes my life so much easier to live! Thank you Lazarus naturals for making such an awesome product!! And for making it so affordable! These products are worth their weight in gold!
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Basically there are a few types of oils. Full spectrum oils are ones that contain terpenes and other compounds. These type of oils tend to work better on specific conditions. Pure CBD is quite hard to come by if you don’t live in a medical or recreational state. There are other oils that also contain THC. The type of oil you need really depends on your medical condition and what you are looking to achieve

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