I purchased Ananda professional full spectrum Extract 600 20/mg/ml CBD oil. I started with .5ml dose the first night right before bedtime. I did not sleep well. I tried the same dose the following evening, and again, poor sleep. I tried it for two more nights and had the same results. I’m very sensitive to steroids and will only use them as a last resort, but the way I felt after taking the CBD oil, reminded me of how poor my sleep is on steroids. Or how vitamin B12 can affect me if I take it too late in the day. I have a lot of inflammation and pain and hoped the CBD oil would help. I am quite surprised at my reaction to it. Anyone else have trouble sleeping when taking it?
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:

CBD Oil Full Spectrum


I just received my second order of CBD oil ever and it defintely won’t be my last from Lazarus. After researching CBD oil brands to my heart’s content, I landed on Lazarus as it seems to be one of the top five best brands. That coupled with being the most economical led me to place my first CBD oil order with them. Their shipping to me (in Portland) the past two orders have always gotten here within two days, and I dig their product — although I don’t have anyting to compare it to. All in all, this is a five star company and you really can’t go wrong.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
THC is the plant compound that makes a person feel ‘high’.  It is naturally found in much higher quantities in marijuana, and in virtually non-existent quantities in hemp. So, when taking a full spectrum cannabinoid extract from hemp, the THC level is so low that you do not feel ‘high’ or groggy.  But, when taking CBD extracted from marijuana, even the “low CBD” strains typically have enough THC to cause someone to feel slightly ‘high’ or at least sleepy or groggy.  And, if its NOT a low CBD strain of marijuana, then watch out, you will most likely experience a pretty significant ‘high’.
It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.
High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).
I suffer from **** from the military and the loss of my 17 year old son which was a very traumatic event and this CBD oil has help lesson my anxiety and stress. I feel I can function better and for the first time in years I can get a full night sleep. I used to lift weights and competed in bodybuilding for 10 years and this has actually helped my joints and mobility, at almost 50 years of age things don’t work like they used too but this CBD oil sure does help. Our dog has anxiety and hip issues and the pet tincture is a solid one-two punch for him and he can get up and down the stairs much better and doesn’t freak out as much when he is on it. You make an amazing product and I am glad I pulled the trigger on the order. I am ordering more and you have a loyal customer now, for me and my pets.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as  a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.
So, the next question is typically:  DO I NEED ALL THESE OTHER CANNABINOIDS TO HELP MY CANCER (or epilepsy, diabetes, etc)?  The answer is “maybe”.  Some people find great results from cannabidiol or CBD alone.  But, more people typically report better results when taking a full spectrum of cannabinoids (sometimes this includes THC, but often times, not).  So, if you’re new to CBD and not sure what direction to go, these reports from people would generally indicate its best to try a full spectrum blend to give you the greatest chance of success.  While having an extract that includes specifically the cannabinoid THC could also increase your chance for success, you have to ask yourself if you want to be ‘high’ all day when taking CBD.  And, you have to consider whether CBD extracted from marijuana is legal where you are.  Because of these two questions, CBD as part of a full spectrum of cannabinoid extracted from hemp, is often times the desired choice.
Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
Broad-spectrum CBD is a little bit of both. Broad-spectrum CBD is full-spectrum CBD without any THC. It offers all the entourage benefits associated with full-spectrum CBD, without any chances of THC being ingested into the body. Broad-spectrum CBD is an excellent choice for individuals that can’t have any traces of THC is their system, whether for legal purposes, passing a drug test, or anything else.
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