The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.
This is my experience with taking CBD 3000mg for the last 6 months. My blood pressure has gone down, I am able to sleep better, the eczema on my hand has disappeared (using a drop or two twice a day on the area). Sort of did an assessment of my body/joints. Everything feels different in a good way. Joints seem to move smoother than before taking CBD. All is great here. Thanks, Lazarus Naturals for such great reasonably priced products.
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.
Some people don’t mind, or even enjoy the natural taste of hemp oil tinctures. For those who are bothered by the distinctive herbal taste of hemp extract, a flavored CBD oil tincture may be better. We’ve selected a variety of both flavored and unflavored CBD oil tinctures in this roundup, and many of the brands selected offer multiple options. If you still can’t stand the flavor of CBD tincture, consider another option like CBD gummies or capsules. Topical CBD is another popular choice, especially if you’re treating body aches or certain skin problems.
Ingredients: Aloe Barbadensis (Aloe Vera) Leaf Juice*, Purified Water, Carthamus Tinctorius (Safflower) Oleosomes, Butyrospermum Parkii (Shae) Butter*, Cocos Nucifera (Coconut) Oil*, Vegetable Glycerin**, Cetearyl Olivate, Sorbitan Olivate**, Mangifera Indica (Mango) Seed Butter*, Lactobacillus Ferment (from Cabbage)**, Lactobacillus, Cocos Nucifera (Coconut) Fruit Extract**, CW Hemp Oil CO2 Extract, Mentha Piperita (Peppermint) Leaf Extract, Arnica Montana Flower Extract, Curcuma Longa (Turmeric) Root Extract, Salix Alba (Willow) Bark Extract, Cimicifuga Racemosa (Black Cohash) Root Extract, Prunus Armeniaca (Apricot) Kernel Oil*, Simmondsia Chinensis (Jojoba) Seed Oil*, Glyceryl Stearate (Palm Oil Derived), Xanthan Gum, Panthenol (Vitamin B5), Tocopheryl Acetate (Vitamin E), Cyamopsis Tetragonolobus (Guar) Gum*, Sodium Benzoate, and Potassium Sorbate.
It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.
Cannabidiol is a plant compound extracted from cannabis (either marijuana or hemp) that is being reported by many to have positive effects on many conditions which have been requiring pharmaceutical solutions, such as cancer, diabetes, epilepsy, anxiety, TMJ, restless leg syndrome and so much more.  CBD extracts from marijuana typically have THC to some extent, thus causing some degree of ‘high’ and may or may not be legal where you live.  CBD extracts from hemp can either by CBD (singluarly) or in full spectrum cannabinoid blends.  Many people find relief with CBD in singular fashion, but best results are typically reported after taking CBD in full spectrum extracts.
The health benefits of full-spectrum hemp go beyond it being a source of CBD. The array of cannabinoids and other natural constituents found in full-spectrum hemp oil work have been shown in studies to work together in what’s referred to as the “entourage effect.” Together, these compounds work harmoniously to magnify their therapeutic properties. The complex mix of cannabinoids, essential nutrients, protein, and healthy fats work synergistically to encourage homeostasis and balance in our health.
Some people don’t mind, or even enjoy the natural taste of hemp oil tinctures. For those who are bothered by the distinctive herbal taste of hemp extract, a flavored CBD oil tincture may be better. We’ve selected a variety of both flavored and unflavored CBD oil tinctures in this roundup, and many of the brands selected offer multiple options. If you still can’t stand the flavor of CBD tincture, consider another option like CBD gummies or capsules. Topical CBD is another popular choice, especially if you’re treating body aches or certain skin problems.
Let’s not forget about terepenes and flavonoids too. While not cannabinoids from hemp, they are compounds found in hemp and other plants. Terpenes are fragrant oils that bind to receptors in the human body and carry a variety of health benefits.* Flavonoids are a group of phytonutrients that serve as cell messengers with their own health-promoting benefits,  

CBD is extracted from both plants in just the same way.  But, when it’s extracted from hemp, it is often times, extracted by itself.  Beyond CBD, there are a host of other plant compounds, called cannabinoids, present in both plants, including THC (more on THC later).  We won’t go into all the other compounds in this article as that would take a book to detail, but a short list of the most common ones are:  CBDA, CBG, CBGA, CBN, Terpenes and Phytonutrients, and THC.  Generally, when CBD is extracted from marijuana, all these compounds are extracted together and the extract is then formulated into various products, thus giving the user this “full spectrum” of cannabinoids.  Generally, when CBD is extracted from hemp, it may or may not include this full spectrum of cannabinoids.  So, this is the first important distinction between CBD from hemp and CBD from marijuana.  When it comes from hemp, it may or may not include all the other cannabinoids.  When it comes from marijuana, it almost always does, including the cannabinoid: THC.  (Note:  ALL Highland Pharms products use a full spectrum of cannabinoid extract.)
Full-spectrum hemp oil refers to when the pure oil extracted from hemp contains all the same cannabinoids and compounds found in the original hemp plant. Unlike isolated or synthetic cannabinoids, full-spectrum hemp oil contains an array of cannabinoids, as well as many essential vitamins and minerals, fatty acids, protein, chlorophyll, fiber, flavonoids, and terpenes.

Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger
This is because these varieties of cannabis contain less THC (or tetrahydrocannabinol), the chemical that produces psychoactivity in humans; in other words, THC is what makes people feel high. CBD offers many of the health benefits of medical marijuana without the high, making it more versatile and less controversial to both users and the community.
The Virgin Hemp Seed Oil that holds the Full Spectrum Hemp CBD Oil together is rich in antioxidants and omega fatty acids, making it an invaluable supplement to any person’s daily diet. This makes the Full Spectrum one of the most nutritious and complete CBD oil products, perfect for those who seek to establish a balanced life through an equally balanced diet.
I have fibromyalgia and piriformious syndrome (severe hip/leg pain) and for the past six months have been dealing with extreme pain and insomnia. Having exhausted all tricks, remedies, doctors, and medications without relief I decided to try Cbd oil. After only two days I have slept like a baby, had hours of continuous deep sleep, sleep app confirmed this. The Hip/leg pain is dulled, but dulled enough that I can do therapy stretches without screaming or crying. The nerve pain from fibro feels like it is asleep! It is the most amazing thing not to feel every nerve in your body after three years of constant pain. The cbd oil does give me a slight tummy ache after taking it but goes away in about an hour. And I do mean slight ache. So far no side effects or interactions. ( Will up date if do)
The health benefits of full-spectrum hemp go beyond it being a source of CBD. The array of cannabinoids and other natural constituents found in full-spectrum hemp oil work have been shown in studies to work together in what’s referred to as the “entourage effect.” Together, these compounds work harmoniously to magnify their therapeutic properties. The complex mix of cannabinoids, essential nutrients, protein, and healthy fats work synergistically to encourage homeostasis and balance in our health.
Our high potency CBD tinctures are carefully extracted and formulated in-house to bring you a high-quality product at a price anyone can afford. Our high potency tinctures are over three times as potent as our Standard Potency CBD tinctures. This product is available in a 15ml bottle containing 750mg, a 60ml bottle containing 3,000mg, or a 120ml bottle containing 6,000mg. We use graduated droppers, so you can easily see how much tincture you are taking. Each ml contains 50mg of CBD. Our high potency CBD tinctures contain our whole plant CBD extract, which feature a spectrum of naturally occurring cannabinoids and terpenes. Our CBD extract is blended with hemp seed oil, fractionated coconut oil, and avocado oil.
Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as  a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.
Ordered this for my restless legs and it’s phenomenal, I have dropped the dosage down to about 6-7 drops a day (so about 15mg) and I have noticed a dramatic improvement in my sleep. I ordered my second small bottle and if the results remain constant I’ll be buying the 60ml next month! I have tried so many different things to help with sleep with no success or inconsistent results. I’m also a powerlifter and I’ve noticed a slight improvement in my recovery.
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger

Tetrahydrocannabinol, or THC, is one of the cannabinoids present in both marijuana and agricultural hemp, and it is the substance responsible for giving a psychoactive effect on the body. It is what gives a user a “high.” The reason why hemp is used over marijuana when creating CBD oil is because of the former’s innate low levels of THC over CBD, making it perfect for CBD oil processing.
A high quality brand of CBD will always provide third-party lab results to their consumers. Some laboratories finds favorable results, while some products fail these tests. These independent labs exist to ensure that CBD oil is everything it claims to be, with a high level of CBD, low THC, and lacking in impurities that can be harmful to consumers.

For our review of the best CBD topicals available online, we focused only on companies which make third-party, independent lab results available to consumers. Lab results are available online, included in the order, or on request. It’s vitally important that consumers know exactly what products they’re consuming: how strong it is, and whether it has any impurities. We also focused on brands with fast, friendly customer service and easy to use websites.
CBD has become quite popular over the last couple of years but despite what you might think it is only one the 100 compounds that have been identified in the Cannabis Sativa L plant. Full spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. Depending on the condition and what you are looking to achieve it can provide a greater effect than CBD alone as all the cannabinoids work together in what is known as the entourage effect (more on that later).
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