The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.
Cannabigerol is known as the stem cell cannabinoid for its role as a precursor to other cannabinoids found in hemp and marijuana. Previously overlooked as a significant cannabinoid, the role of CBG is becoming better understood, and companies like Medical Marijuana, Inc.’s AXIM® Biotechnologies are starting to research its potential. Because most CBG is transformed into other cannabinoids like CBD or THC by the cannabis plant, natural CBG levels are low in most processed cannabis plants.
I have fibromyalgia and piriformious syndrome (severe hip/leg pain) and for the past six months have been dealing with extreme pain and insomnia. Having exhausted all tricks, remedies, doctors, and medications without relief I decided to try Cbd oil. After only two days I have slept like a baby, had hours of continuous deep sleep, sleep app confirmed this. The Hip/leg pain is dulled, but dulled enough that I can do therapy stretches without screaming or crying. The nerve pain from fibro feels like it is asleep! It is the most amazing thing not to feel every nerve in your body after three years of constant pain. The cbd oil does give me a slight tummy ache after taking it but goes away in about an hour. And I do mean slight ache. So far no side effects or interactions. ( Will up date if do)
Every CBD product should make third-party lab results available, either online, in their packaging, or by request. At minimum, each tincture here offers lab results showing the levels of cannabinoids like CBD and THC, while others offer additional tests. The more information available to consumers the better. At the same time, we admit it isn’t always easy for newcomers to interpret these lab tests.
Marijuana & hemp are both cannabis sativa (and some marijuana is cannabis indica). But “industrial hemp” (the only source of CBD lawful in all 50 states, thanks to the Federal Farm Bill’s exemption of it from the Controlled Substances Act) CBD extract products are lawful in all 50 states, can be sold on the open market at any store (not just a licensed dispensary) or online to anyone over 18–regardless of the customer’s or mfr’s state’s medical or recreational weed laws.
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In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.