In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.
While there is much debate on which form is better, this 2015 study (http://file.scirp.org/pdf/PP_2015021016351567.pdf) leans in favor of Full Spectrum products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) instead of Full Spectrum.

CBD has been producing a whole lot of buzz in the health community of late – but perhaps not the kind of buzz you might expect from a cannabinoid. Since you’re reading this, you’ve probably heard of CBD and its many touted benefits. From chronic pain to mental health, CBD has the potential to alleviate an astonishing number of ailments. But like many, you might be fuzzy on the details. Consider this your primer on all things CBD.
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.
There are over 80+ beneficial compounds that are naturally found in hemp. Collectively these compounds are called cannabinoids. When you take hemp oil, you support your endocannabinoid system which explains why people all over the world are using hemp oil to help calm the effects of temporary inflammation, ease stress and everyday discomfort, and improve the quality of sleep.
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
Hi Diane, we wanted to give some feedback on this subject. Our products are made from hemp which is naturally low in THC, however, they do contain federally acceptable levels of THC. Our full spectrum products contain up to 0.3% THC by weight. Our isolate based tinctures have an undetectable level of THC per our testing standards. However, we do not recommend CBD products for those who are worried about drug testing as there are many shared compounds between hemp and marijuana that could cause a false positive.

Not to be confused with its botanical cousin marijuana, premium hemp oil is extracted from the hemp plant. While hemp and marijuana share many of the same beneficial compounds—cannabinoids, terpenes, and antioxidant flavonoids—there is one important difference. Hemp has only trace amounts of THC, the psychoactive compound found in high amounts in marijuana, so there is no “high” when taking full spectrum hemp oil, just health benefits.

Another field in which CBD is creating a buzz is in the area of mood disorders like anxiety and depression. Both conditions have been treated with a variety of medications, courtesy of Big Pharma, that have had varying levels of success. Again, the long list of side effects can be off-putting to someone who just wants to get through the day without the sweaty tension of anxiety or the gray haze of depression.
In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.

Tetrahydrocannabinol is the most abundant cannabinoid in most medical and recreational marijuana strains. However, in hemp THC is a minor constituent and appears only in trace amounts under 0.3% by dry weight, as required by the U.S. government for hemp products. THC mimics the action of anandamide, a neurotransmitter naturally produced in the human body, and binds to CB1 receptors in the endocannabinoid system found mostly in the brain. The extremely low levels of THC in hemp make hemp oil non-psychoactive and safe for all ages to use.


WOW!! Blown away! I have suffered from pain for over 7 years, I can’t remember what it felt like to have pain that was less then off the charts, and i have a high tolerance for pain, So on hope and and a prayer I decided to try your The High Potency and WOW..I am blown away at how within a short time, my pain was down to a 2!! i was literally sobbing with relief after the first time using your product!! bless you all for ALL you do!!
It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.
In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.
Received my first order about a month ago. Wanted to try it before giving feedback. I would frequently wake up at night with my hands just throbbing. I ordered the high potency tropical isolate. I have been taking a total of 60mg a day split into two doses. It has greatly reduced the pain in my hands, no longer waking up at night from the pain. I have also noticed it has a calming effect. Order was processed immediately and shipped right away with tracking. I am going to order the full spectrum when it is time for a refill as I can see it may work better for my needs. I would highly recommend LN and their products.
It sounds like the title of a children’s book, but like so much else that you learned in kindergarten, it’s true. Everyone’s body is different – but everyone’s endocannabinoid system is really unique. For reasons we don’t fully understand, receptors in the endocannabinoid system don’t respond predictably to cannabinoids from person to person. This lack of a predictable response makes standard dosing tricky.
After starting with another 300 mg isolate from another brand, I ordered a 225 regular tincture LN. While some like the full spectrum flavor, I can’t handle putting it under my tonge (the most efficient way to absorb it as opposed to swallowing it, ingesting it, which takes a higher dose for the same effect). I ordered the wintermint 750 high potency which has really helped me with back pain from an injured disc, and arthritis in my hip. I’m not pain free, but it is dramatically better. And I can put it under my tongue. I would like to take a full spectrum high potency that tastes like the isolate. How about it, guys? Please. Could you email me?
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.

I purchased Ananda professional full spectrum Extract 600 20/mg/ml CBD oil. I started with .5ml dose the first night right before bedtime. I did not sleep well. I tried the same dose the following evening, and again, poor sleep. I tried it for two more nights and had the same results. I’m very sensitive to steroids and will only use them as a last resort, but the way I felt after taking the CBD oil, reminded me of how poor my sleep is on steroids. Or how vitamin B12 can affect me if I take it too late in the day. I have a lot of inflammation and pain and hoped the CBD oil would help. I am quite surprised at my reaction to it. Anyone else have trouble sleeping when taking it?


We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).

In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.
The most abundant cannabinoid in hemp oil, making up over 90% of the cannabinoid content, cannabidiol or CBD is non-psychoactive and is the focus of the benefits from hemp oil. CBD has little affinity for CB1 or CB2 receptors, the main points of interaction for cannabinoids in the endocannabinoid system, and instead acts as an indirect antagonist of cannabinoid agonists, possibly allowing CBD to temper the high caused by THC. Our Gold Label RSHO™ is almost 25% CBD, making up most of oil’s weight. All other cannabinoids come in under 0.4% by weight.
I use plus CBD brand for my patients and myself.It’s a fantastic company with a great reliable product. They have the biggest share of retail outlets in the country so they have to be priced right and labeled properly. They also have GRAS rating. That means generally regarded as safe. They are the only CBD company to do the research and spend the money to get that rating. I love the gummies.
With 250 mg of CBD in the 1 oz bottle and twice that in the 2 oz bottle, the Full Spectrum Hemp CBD Oil by Bluebird Botanicals is powerful and wellness improving. CBD has been proven to be effective at soothing the senses and shows promise as a well-balanced wellness enhancer. On top of that, CBD has been proven to have virtually zero known side effects and absolutely no psychoactive properties. This makes CBD completely safe and legal to purchase and use across all 50 states as well as in more than 40 countries worldwide. The Full Spectrum Hemp CBD Oil contains virtually zero THC, so you can consume it with no worries of psychotropic effects.
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