The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
I use plus CBD brand for my patients and myself.It’s a fantastic company with a great reliable product. They have the biggest share of retail outlets in the country so they have to be priced right and labeled properly. They also have GRAS rating. That means generally regarded as safe. They are the only CBD company to do the research and spend the money to get that rating. I love the gummies.
This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.

CBD has become quite popular over the last couple of years but despite what you might think it is only one the 100 compounds that have been identified in the Cannabis Sativa L plant. Full spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. Depending on the condition and what you are looking to achieve it can provide a greater effect than CBD alone as all the cannabinoids work together in what is known as the entourage effect (more on that later).
While cannabidiol (CBD) is all the rage at present, it is often hard to understand what you are getting. Furthermore, with so many different CBD products on the market it’s hard to tell which are full spectrum, which are not and which products are made from CBD cannabis or CBD hemp.  In this article we will try to clear up any confusion, focusing the major part of the post around Full Spectrum CBD oil.
Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
I suffer from **** from the military and the loss of my 17 year old son which was a very traumatic event and this CBD oil has help lesson my anxiety and stress. I feel I can function better and for the first time in years I can get a full night sleep. I used to lift weights and competed in bodybuilding for 10 years and this has actually helped my joints and mobility, at almost 50 years of age things don’t work like they used too but this CBD oil sure does help. Our dog has anxiety and hip issues and the pet tincture is a solid one-two punch for him and he can get up and down the stairs much better and doesn’t freak out as much when he is on it. You make an amazing product and I am glad I pulled the trigger on the order. I am ordering more and you have a loyal customer now, for me and my pets.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
Since our beginning, Medical Marijuana, Inc. has been striving to bring the health benefits of cannabinoids to the lives of as many people as possible through cannabinoid hemp oil supplements. With our knowledge of cannabinoids and the endocannabinoid system just scratching the surface of what’s possible, there is plenty of potential to find new uses for the myriad of cannabinoids available to us.

While there is much debate on which form is better, this 2015 study (http://file.scirp.org/pdf/PP_2015021016351567.pdf) leans in favor of Full Spectrum products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) instead of Full Spectrum.
This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.

You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.

Yes! In addition to the rigorous quality assurance testing that Calm Premium Hemp Oil undergoes before it goes in the bottle, it is also sent out for independent analysis. This testing is conducted at ProVerde Labs, and shows that Calm Premium Hemp Oil is a full spectrum hemp oil rich in cannabinoids and terpenes with zero THC. You can view the lab certificate online > click here
I have fibromyalgia and piriformious syndrome (severe hip/leg pain) and for the past six months have been dealing with extreme pain and insomnia. Having exhausted all tricks, remedies, doctors, and medications without relief I decided to try Cbd oil. After only two days I have slept like a baby, had hours of continuous deep sleep, sleep app confirmed this. The Hip/leg pain is dulled, but dulled enough that I can do therapy stretches without screaming or crying. The nerve pain from fibro feels like it is asleep! It is the most amazing thing not to feel every nerve in your body after three years of constant pain. The cbd oil does give me a slight tummy ache after taking it but goes away in about an hour. And I do mean slight ache. So far no side effects or interactions. ( Will up date if do)
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).

I have tried 2 other “5 star” companies high potency oils and Lazarus is by far the best in terms of results, taste, and value/cost. Your product is phenomenal, as is the customer service. I get nervous to see product out of stock fairly often because I love it so much and don’t want to be left without something so helpful. Hoping it’s nothimg to worry about. In any event, thank you!!!
There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.
Received my first order about a month ago. Wanted to try it before giving feedback. I would frequently wake up at night with my hands just throbbing. I ordered the high potency tropical isolate. I have been taking a total of 60mg a day split into two doses. It has greatly reduced the pain in my hands, no longer waking up at night from the pain. I have also noticed it has a calming effect. Order was processed immediately and shipped right away with tracking. I am going to order the full spectrum when it is time for a refill as I can see it may work better for my needs. I would highly recommend LN and their products.
While cannabidiol (CBD) is all the rage at present, it is often hard to understand what you are getting. Furthermore, with so many different CBD products on the market it’s hard to tell which are full spectrum, which are not and which products are made from CBD cannabis or CBD hemp.  In this article we will try to clear up any confusion, focusing the major part of the post around Full Spectrum CBD oil.
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