When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
CBD is extracted from both plants in just the same way.  But, when it’s extracted from hemp, it is often times, extracted by itself.  Beyond CBD, there are a host of other plant compounds, called cannabinoids, present in both plants, including THC (more on THC later).  We won’t go into all the other compounds in this article as that would take a book to detail, but a short list of the most common ones are:  CBDA, CBG, CBGA, CBN, Terpenes and Phytonutrients, and THC.  Generally, when CBD is extracted from marijuana, all these compounds are extracted together and the extract is then formulated into various products, thus giving the user this “full spectrum” of cannabinoids.  Generally, when CBD is extracted from hemp, it may or may not include this full spectrum of cannabinoids.  So, this is the first important distinction between CBD from hemp and CBD from marijuana.  When it comes from hemp, it may or may not include all the other cannabinoids.  When it comes from marijuana, it almost always does, including the cannabinoid: THC.  (Note:  ALL Highland Pharms products use a full spectrum of cannabinoid extract.)
On a molecular level, all classes of cannabinoid are derived from the cannabinoid cannabigerol (CBG). Cannabinoids are changed from their original acid forms by decarboxylation through heat, light, or alkaline conditions, allowing them to interact fully with the endocannabinoid system. Learn more about all the cannabinoids found in our full spectrum hemp oil below:
I can’t assist with what you need, but I can tell you that I am a cancer survivor ( 15 years), with Chronic Fibro, arthritis and nerve damage . I was on prescribed pain meds for a long time. CBD has been a life saver. I have tried several of the above. For me, Bluebird is the best so far of them all. In terms of effectiveness , its heads and tails ( no pun intended) above the rest. They do have a program as well , yes. They are pricey . I also like Lazarus’s 25 mg Capsules as well.
Ingredients: 100 mg Hemp Flower Extract, Organic Coconut Oil, Organic Shea Butter, Cocoa Butter, Beeswax, Organic Menthol Crystals, Boswellia Extract Powder, White Willow Bark Extract, Organic Cayenne, Organic Calendula Flowers, Organic Ginger, Arnica Oil, Capsicum Oil, Sunflower Oil, Essential Oils: Wintergreen, Organic Eucalyptus, Peppermint, Lavender, and Ginger
You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
Cannabigerol is known as the stem cell cannabinoid for its role as a precursor to other cannabinoids found in hemp and marijuana. Previously overlooked as a significant cannabinoid, the role of CBG is becoming better understood, and companies like Medical Marijuana, Inc.’s AXIM® Biotechnologies are starting to research its potential. Because most CBG is transformed into other cannabinoids like CBD or THC by the cannabis plant, natural CBG levels are low in most processed cannabis plants.
While there is much debate on which form is better, this 2015 study (http://file.scirp.org/pdf/PP_2015021016351567.pdf) leans in favor of Full Spectrum products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) instead of Full Spectrum.
I have tried 2 other “5 star” companies high potency oils and Lazarus is by far the best in terms of results, taste, and value/cost. Your product is phenomenal, as is the customer service. I get nervous to see product out of stock fairly often because I love it so much and don’t want to be left without something so helpful. Hoping it’s nothimg to worry about. In any event, thank you!!!

I just got mine delivered on Thursday and I will say this is the best thing I’ve spent money on in a while!! As a former THC user, there is a small chance that I will go back to using that again (at least until my state legalizes it). I literally get the same relief using CBD as I did with THC, but minus the psychoactive effects, which I don’t miss by the way. I feel alert yet relaxed all at the same time. The dosage recommends 1mL, but I’m good with just .5mL. I will be placing another order very soon. This stuff has changed my life!! Thank you Lazarus Naturals…total game changer!!
This is a hugely beneficial effect of CBD. Free radicals are the culprits when it comes to oxidative damage and inflammation. But CBD’s antioxidant properties can help to combat the negative effects of everyday exposure to elements that increase the production of free radicals. These elements include pervasive, but hugely unsurprising, things like:
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.

Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as  a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.

Full-spectrum hemp oil refers to when the pure oil extracted from hemp contains all the same cannabinoids and compounds found in the original hemp plant. Unlike isolated or synthetic cannabinoids, full-spectrum hemp oil contains an array of cannabinoids, as well as many essential vitamins and minerals, fatty acids, protein, chlorophyll, fiber, flavonoids, and terpenes.
Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.
While full spectrum CBD has ultimately proven to be more effective than CBD Isolate and can be used to effectively treat a wide variety of ailments, it does not discredit the effectiveness of CBD Isolate. There are a wide variety of situations when CBD isolate would be preferred over Full Spectrum CBD. For example, you may not necessarily need the full capabilities of Full Spectrum CBD, or if you aren’t legally allowed to use THC. It is also important to note that other cannabinoids may cause negative reactions when isolated CBD wouldn’t (if the condition you are suffering from is critical, we definitely advise you speak to a medical consultant before trying out any version of CBD).
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