The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:

CBD Oil Full Spectrum


It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.
So a full spectrum decarb got higher points than isolate (“decarb” just refers to the process of decarboxylation which turns raw CBD into activated CBD). We also gave more points to companies with a “broad spectrum” tincture. Broad spectrum CBD oil includes a range of other cannabinoids, but minus the THC – which is generally what people using isolates are trying to avoid.
I wana take a minute to thank Lazarusnaturals for such great products. I have been suffering from ******,***** and ***** for years and have not been able to find relief from my pain medication,I know I’ll never be pain free as long as I’m breathing but CBD is pretty damn close to giving me my life back an being 90% pain free! I didn’t expect much from the CBD oil cuz there isn’t any THC (psychoactive) in it so I wasn’t getting excited lol but guess what?!! I’m super excited cuz this stuff works. Don’t knock it til you try it,if you suffer from pain do yourself a favor and order some CBD oil I promise you it will take the edge off.Im ordering my 3rd bottle now cuz this stuff works better then pain pills if you’re suffering from pain.
I can’t say enough good things about LN CBD tinctures. The 750mg high potency is a wonderful tasting full spectrum tincture that helps me with back pain, ***** and overall restlessness. I’m so thankful I found LN. I’ve compared the prices of all the truly legitimate CBD sellers (via r/CBD reddit group) and you get the best product per your dollar when you buy LN.
Mimi says the effective oils are made from the marijuana plant, not hemp. Why are you rating only hemp oils? Are hemp oils the only oils that do not have any THC? The other question that arises is the difference between ml and mg in measuring the strength of these oils. They are quoted as ml, but there is the question of the “density” limit of 95mg? Very confusing.
There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
Hi Diane, we wanted to give some feedback on this subject. Our products are made from hemp which is naturally low in THC, however, they do contain federally acceptable levels of THC. Our full spectrum products contain up to 0.3% THC by weight. Our isolate based tinctures have an undetectable level of THC per our testing standards. However, we do not recommend CBD products for those who are worried about drug testing as there are many shared compounds between hemp and marijuana that could cause a false positive.
In short, Cannabidiol – or CBD – is a cannabis compound that has many therapeutic benefits. Usually extracted from the leaves and flowers of hemp plants – though marijuana can also be a source – CBD oil is then incorporated into an array of marketable products. These products vary from the most common, like sublingual oils and topical lotions, to the less common (think CBD lattes). Basically, if you can dream it, you can buy it.
Although low, the original amount of THC present in hemp may still cause a certain level of psychoactive effects when processed incorrectly. Remember, CBD oil is made from the extracts of hundreds, even thousands, of hemp plants, therefore, no matter how small a percentage of THC there is in hemp, it may still have a high concentration on CBD oils that have been processed poorly, especially since the equipment needed to properly process CBD oil from hemp can be costly.
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
Ingredients: Aloe Barbadensis (Aloe Vera) Leaf Juice*, Purified Water, Carthamus Tinctorius (Safflower) Oleosomes, Butyrospermum Parkii (Shae) Butter*, Cocos Nucifera (Coconut) Oil*, Vegetable Glycerin**, Cetearyl Olivate, Sorbitan Olivate**, Mangifera Indica (Mango) Seed Butter*, Lactobacillus Ferment (from Cabbage)**, Lactobacillus, Cocos Nucifera (Coconut) Fruit Extract**, CW Hemp Oil CO2 Extract, Mentha Piperita (Peppermint) Leaf Extract, Arnica Montana Flower Extract, Curcuma Longa (Turmeric) Root Extract, Salix Alba (Willow) Bark Extract, Cimicifuga Racemosa (Black Cohash) Root Extract, Prunus Armeniaca (Apricot) Kernel Oil*, Simmondsia Chinensis (Jojoba) Seed Oil*, Glyceryl Stearate (Palm Oil Derived), Xanthan Gum, Panthenol (Vitamin B5), Tocopheryl Acetate (Vitamin E), Cyamopsis Tetragonolobus (Guar) Gum*, Sodium Benzoate, and Potassium Sorbate.
Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).

On a molecular level, all classes of cannabinoid are derived from the cannabinoid cannabigerol (CBG). Cannabinoids are changed from their original acid forms by decarboxylation through heat, light, or alkaline conditions, allowing them to interact fully with the endocannabinoid system. Learn more about all the cannabinoids found in our full spectrum hemp oil below:


These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”

In short, Cannabidiol – or CBD – is a cannabis compound that has many therapeutic benefits. Usually extracted from the leaves and flowers of hemp plants – though marijuana can also be a source – CBD oil is then incorporated into an array of marketable products. These products vary from the most common, like sublingual oils and topical lotions, to the less common (think CBD lattes). Basically, if you can dream it, you can buy it.

Hi Diane, we wanted to give some feedback on this subject. Our products are made from hemp which is naturally low in THC, however, they do contain federally acceptable levels of THC. Our full spectrum products contain up to 0.3% THC by weight. Our isolate based tinctures have an undetectable level of THC per our testing standards. However, we do not recommend CBD products for those who are worried about drug testing as there are many shared compounds between hemp and marijuana that could cause a false positive.


You may have read or heard in the news all the reports of people wanting to take CBD Oil for many ailments, some of which are cancer, epilepsy, chronic pain, TMJ, anxiety and diabetes.  And, many people are reporting some pretty fantastic improvements to their conditions after taking these oils.   The first thing most people want to know is: IS THERE ANY DIFFERENCE BETWEEN CANNABIDIOL FROM HEMP AND CANNABIDIOL FROM MARIJUANA?  And, the short answer is “no”; molecularly, CBD is CBD.  But, there are generally some differences in the CBD Extracts.  Let me explain this a bit further.
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
There are over 80+ beneficial compounds that are naturally found in hemp. Collectively these compounds are called cannabinoids. When you take hemp oil, you support your endocannabinoid system which explains why people all over the world are using hemp oil to help calm the effects of temporary inflammation, ease stress and everyday discomfort, and improve the quality of sleep.
The first step to finding your correct CBD dosage is getting as much information as you can about the product you’re using. What is the concentration of CBD? Are there third-party lab tests that can confirm that? The CBD industry is still mainly a grassroots therapeutic movement, and as such, largely unregulated. Concentration and purity levels can differ greatly depending on the manufacturing process.  

When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
Many people are familiar with cannabidiol (CBD), which is found in highly concentrated amounts in our products, but there are actually dozens of cannabinoids found in hemp, which have shown many benefits in studies. We choose to make all our products with full-spectrum hemp oil, which includes all of the cannabinoids found in the plant, so you don’t miss out on any of the benefits.

After starting with another 300 mg isolate from another brand, I ordered a 225 regular tincture LN. While some like the full spectrum flavor, I can’t handle putting it under my tonge (the most efficient way to absorb it as opposed to swallowing it, ingesting it, which takes a higher dose for the same effect). I ordered the wintermint 750 high potency which has really helped me with back pain from an injured disc, and arthritis in my hip. I’m not pain free, but it is dramatically better. And I can put it under my tongue. I would like to take a full spectrum high potency that tastes like the isolate. How about it, guys? Please. Could you email me?
When looking at isolate, it is important to verify the purity. While many are in the 99.9+% range with no identifiable amounts of THC, there are lower purity ones (such as 99.5% or lower) that may still have trace amounts that show up on the labs. This small amount is typically negligible, and is nowhere near the amount usually found in Full Spectrum products. But it’s still something to be aware of for those seeking the purest they can find.
I have also called a couple places to get some input about what we may need, but they all said they cannot give advice. Then HOW do we know what to get. As for MOST of us, we are by no means well off. Quite the opposite, in fact. So to keep “trying” a bunch of different ones is not an option. Blue Bird in CO give discounts to low income, so would like to use their products if possible.
Seeing how well this product worked, I went on to sample other brands and various products of CBD and Hemp Extracts- This resulted as a waste of time and money because every top brand I’d read about online was either complete garbage (one brand starting with the letter E ending with L made me violently ill and I can’t even uncap the bottle without being made to feel sick) OR there was no discernible difference between those products and Lazarus. Keeping these facts in mind, there is absolutely without a doubt- no other product of CBD oil that can compete with these guys(Lazarus Naturals).

CBD Oil THC Free

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