While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.

It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.


After starting with another 300 mg isolate from another brand, I ordered a 225 regular tincture LN. While some like the full spectrum flavor, I can’t handle putting it under my tonge (the most efficient way to absorb it as opposed to swallowing it, ingesting it, which takes a higher dose for the same effect). I ordered the wintermint 750 high potency which has really helped me with back pain from an injured disc, and arthritis in my hip. I’m not pain free, but it is dramatically better. And I can put it under my tongue. I would like to take a full spectrum high potency that tastes like the isolate. How about it, guys? Please. Could you email me?
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”
Another quality of a good CBD oil is that it is manufactured using the whole plant. CBD Isolates are becoming increasingly popular, but in reality, it is a cheaper material than whole plant extracts.  Using the whole plant, rather than using only one part, ensures that the oil contains not just CBD, but also the full range of primary and secondary constituents of the hemp plant. These include terpenes, flavonoids, and other cannabinoids that are generally believed to work synergistically with CBD, making the benefits exponentially higher than CBD alone.
Based on the comparison above, full spectrum hemp oil is more effective than CBD isolate, making it highly recommended for patients interested in holistic approaches to medicinal cannabis treatments. Hemp oil is an extremely potent source of CBD (responsible for a large bulk of the oil’s cannabinoid profile). To fully reap CBD oil benefits, one should explore the different mediums of the compound available on the market today.
Like any manufactured product, one of the best ways to ensure quality is to use high-quality materials. This is especially important in CBD oil because of the hemp plant’s characteristic as  a “hyperaccumulator.” This means that the hemp plant easily absorbs anything that is present in the ground that it was cultivated and farmed. If a hemp plant grew on rich soil, the resulting plant will be of high quality that can produce CBD oil in the same high-quality as well.
Let’s not forget about terepenes and flavonoids too. While not cannabinoids from hemp, they are compounds found in hemp and other plants. Terpenes are fragrant oils that bind to receptors in the human body and carry a variety of health benefits.* Flavonoids are a group of phytonutrients that serve as cell messengers with their own health-promoting benefits,  
Every CBD product should make third-party lab results available, either online, in their packaging, or by request. At minimum, each tincture here offers lab results showing the levels of cannabinoids like CBD and THC, while others offer additional tests. The more information available to consumers the better. At the same time, we admit it isn’t always easy for newcomers to interpret these lab tests.
When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
I was highly impressed with this product, and honestly surprised. I have tried many different cbd products, from many different companies, only to find them to be mediocre at best. Lazarus naturals, by far has the most effective cbd I’ve yet to try. With only a 1ml serving, I was able to nullify my knee and foot pain after a 10 hour shift of non-stop standing and walking. Will for sure be a returning customer.

High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.

Being a hyperaccumulator also has drawbacks: If a hemp plant that is used in production of CBD oil was cultivated in a land that is rich in heavy metals such as mercury and lead, the resulting oils will also reflect the amount of heavy metals absorbed by the plant, making it unsafe for humans to consume, especially children or others who are extremely vulnerable to toxins.
I am very impressed with this CBD oil, out of three I’ve tried. Recently injured my neck and/or trapezius muscle with heavy weights. The pain was pretty severe and limited my mobility during the day and my sleep at night, no matter the position. This CBD oil really muted the discomfort and allowed me so much better sleep. I’ll keep using this one. Thank you so much Lazarus for crafting this miracle product and also, for the veterans discount. God bless!
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
Our full spectrum CBD tincture is 100% natural and consistently 3rd party lab-tested to ensure quality. Full spectrum tinctures contain CBD and the other naturally-occurring cannabinoids and terpenes in the hemp plant, so you get all the benefits cannabis can provide, with none of the high. Tinctures are a unique and easily-absorbed substance, so you can feel relief faster.
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