CBD is extracted from both plants in just the same way.  But, when it’s extracted from hemp, it is often times, extracted by itself.  Beyond CBD, there are a host of other plant compounds, called cannabinoids, present in both plants, including THC (more on THC later).  We won’t go into all the other compounds in this article as that would take a book to detail, but a short list of the most common ones are:  CBDA, CBG, CBGA, CBN, Terpenes and Phytonutrients, and THC.  Generally, when CBD is extracted from marijuana, all these compounds are extracted together and the extract is then formulated into various products, thus giving the user this “full spectrum” of cannabinoids.  Generally, when CBD is extracted from hemp, it may or may not include this full spectrum of cannabinoids.  So, this is the first important distinction between CBD from hemp and CBD from marijuana.  When it comes from hemp, it may or may not include all the other cannabinoids.  When it comes from marijuana, it almost always does, including the cannabinoid: THC.  (Note:  ALL Highland Pharms products use a full spectrum of cannabinoid extract.)
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).
While it is clear that full spectrum CBD may be more effective than isolate CBD, even at lower dosages, it may have some drawbacks. Full spectrum vs regular CBD comes down to this drawback for many people. If full spectrum CBD oil is not an option for you due to your obligations or lifestyle, this can help you make your decision more easily for sure.
I can not recommend this highly enough, as well as Lazarus Naturals in general. This is theee best value on cbd I’ve seen, and it’s the most healthy because of the extraction process and the oils it’s diluted with. I would give 100 stars if I could. Thank you, Lazarus Naturals!!! And thank you for helping people with disabilities and low income such as myself. I am now a forever-loyal-customer!

Essential fatty acids are necessary for maintaining heart and cardiovascular health. The two primary essential fatty acids — Omega 3 and Omega 6 — are ideally consumed at a ratio of around 3:1. Unfortunately, in the typical American diet, that ratio is close to 25:1. Full-spectrum hemp oil offers the two essential fatty acids in the optimal 3:1 ratio.

It’s a truism to state that pain is an inevitable part of life. And it’s true that we all, from time to time, experience pain that is short-lived and treatable. But those who deal with chronic pain know the debilitating, life-sucking reality of this condition. And traditional medications often come with long lists of side effects which can be as debilitating as the pain itself.
Well For Starters,I Wanna Thank Lazarus for Honoring me and Giving me the Discount as A Qualification,And I Ordered the 6000 mg Bottle,I will Never Regret this,I can Take .25 ml and Be as Calm as a Cucumber,And Not Have to Take the Percocet Pain meds I was on,If Your Truly Asking Your Self Should I buy or not,I’m Gonna Say this,I’ve Bought Alot of Junk in my days,But this is The Real Deal,It Will Take good care of You,God Bless you Lazarus,Thank You For Taking Good Care of Us Veterans
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.

On a molecular level, all classes of cannabinoid are derived from the cannabinoid cannabigerol (CBG). Cannabinoids are changed from their original acid forms by decarboxylation through heat, light, or alkaline conditions, allowing them to interact fully with the endocannabinoid system. Learn more about all the cannabinoids found in our full spectrum hemp oil below:

This may be a good place to point out that not all CBD products are created equal. The industry is still largely unregulated, and the quality and quantity of CBD in a given product will vary wildly. Third party testing definitely helps to monitor companies’ claims, but it’s still up to you as the consumer to do your homework on the best CBD products.


Based on the comparison above, full spectrum hemp oil is more effective than CBD isolate, making it highly recommended for patients interested in holistic approaches to medicinal cannabis treatments. Hemp oil is an extremely potent source of CBD (responsible for a large bulk of the oil’s cannabinoid profile). To fully reap CBD oil benefits, one should explore the different mediums of the compound available on the market today.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.

Tetrahydrocannabinol, or THC, is one of the cannabinoids present in both marijuana and agricultural hemp, and it is the substance responsible for giving a psychoactive effect on the body. It is what gives a user a “high.” The reason why hemp is used over marijuana when creating CBD oil is because of the former’s innate low levels of THC over CBD, making it perfect for CBD oil processing.


CBD (cannabidol) is gaining popularity as a hot term in the health and wellness world —and will continue to do so as more people come to understand how beneficial* it can be to the human body.  But CBD isn’t the only phytocompound we’re excited about in our Charlotte’s Web hemp extract. That’s because our extract is more than just CBD.  Among the beneficial* compounds that come from plants, we have more than 80 of them. 

While it is clear that full spectrum CBD may be more effective than isolate CBD, even at lower dosages, it may have some drawbacks. Full spectrum vs regular CBD comes down to this drawback for many people. If full spectrum CBD oil is not an option for you due to your obligations or lifestyle, this can help you make your decision more easily for sure.
Seeing how well this product worked, I went on to sample other brands and various products of CBD and Hemp Extracts- This resulted as a waste of time and money because every top brand I’d read about online was either complete garbage (one brand starting with the letter E ending with L made me violently ill and I can’t even uncap the bottle without being made to feel sick) OR there was no discernible difference between those products and Lazarus. Keeping these facts in mind, there is absolutely without a doubt- no other product of CBD oil that can compete with these guys(Lazarus Naturals).
In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.
Basically there are a few types of oils. Full spectrum oils are ones that contain terpenes and other compounds. These type of oils tend to work better on specific conditions. Pure CBD is quite hard to come by if you don’t live in a medical or recreational state. There are other oils that also contain THC. The type of oil you need really depends on your medical condition and what you are looking to achieve
Marijuana & hemp are both cannabis sativa (and some marijuana is cannabis indica). But “industrial hemp” (the only source of CBD lawful in all 50 states, thanks to the Federal Farm Bill’s exemption of it from the Controlled Substances Act) CBD extract products are lawful in all 50 states, can be sold on the open market at any store (not just a licensed dispensary) or online to anyone over 18–regardless of the customer’s or mfr’s state’s medical or recreational weed laws.
Ordered this for my restless legs and it’s phenomenal, I have dropped the dosage down to about 6-7 drops a day (so about 15mg) and I have noticed a dramatic improvement in my sleep. I ordered my second small bottle and if the results remain constant I’ll be buying the 60ml next month! I have tried so many different things to help with sleep with no success or inconsistent results. I’m also a powerlifter and I’ve noticed a slight improvement in my recovery.

CBD is found bonded naturally to fats in many organic sources, most notably within a human mother’s breast milk.  This allows the P-450 enzyme in the liver to naturally break down CBD to then utilize it within the endocannabinoid system.  We replicate this process, in the most organic way we can, through bonding the hemp-derived cannabinoids in MCT Coconut oil.  We want your experience using our hemp oil to be easy and accurate!


When CBD is in isolate form, it is separated from other cannabis compounds in the source plant. It was previously believed that CBD isolates were more potent and concentrated than full spectrum CBD. This assertion was eventually debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the 2015 study, researchers were able to prove that full spectrum CBD is capable of offering greater levels of relief, as higher doses were administered to mice. By comparison, the group that was given CBD isolate did not experience the same level of relief at higher doses.
Yes! In addition to the rigorous quality assurance testing that Calm Premium Hemp Oil undergoes before it goes in the bottle, it is also sent out for independent analysis. This testing is conducted at ProVerde Labs, and shows that Calm Premium Hemp Oil is a full spectrum hemp oil rich in cannabinoids and terpenes with zero THC. You can view the lab certificate online > click here
You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).

Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
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