These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”
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There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.
It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.
On a molecular level, all classes of cannabinoid are derived from the cannabinoid cannabigerol (CBG). Cannabinoids are changed from their original acid forms by decarboxylation through heat, light, or alkaline conditions, allowing them to interact fully with the endocannabinoid system. Learn more about all the cannabinoids found in our full spectrum hemp oil below:
CBD has become quite popular over the last couple of years but despite what you might think it is only one the 100 compounds that have been identified in the Cannabis Sativa L plant. Full spectrum CBD oil, unlike CBD isolate products, includes a wide range of cannabinoids present in the cannabis or hemp plant. Depending on the condition and what you are looking to achieve it can provide a greater effect than CBD alone as all the cannabinoids work together in what is known as the entourage effect (more on that later).
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.

While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
With 250 mg of CBD in the 1 oz bottle and twice that in the 2 oz bottle, the Full Spectrum Hemp CBD Oil by Bluebird Botanicals is powerful and wellness improving. CBD has been proven to be effective at soothing the senses and shows promise as a well-balanced wellness enhancer. On top of that, CBD has been proven to have virtually zero known side effects and absolutely no psychoactive properties. This makes CBD completely safe and legal to purchase and use across all 50 states as well as in more than 40 countries worldwide. The Full Spectrum Hemp CBD Oil contains virtually zero THC, so you can consume it with no worries of psychotropic effects.
The Virgin Hemp Seed Oil that holds the Full Spectrum Hemp CBD Oil together is rich in antioxidants and omega fatty acids, making it an invaluable supplement to any person’s daily diet. This makes the Full Spectrum one of the most nutritious and complete CBD oil products, perfect for those who seek to establish a balanced life through an equally balanced diet.
Wow that shipping was fast! I was buying cbd from another place and they were rude and sarcastic to me in an email so i decided to try this company. I got my order today and product smells great very earthy i like the measurments are right on the dropper for me so im not counting drops, prices are great customer service was great and shipping was super quick.
Tetrahydrocannabinol is the most abundant cannabinoid in most medical and recreational marijuana strains. However, in hemp THC is a minor constituent and appears only in trace amounts under 0.3% by dry weight, as required by the U.S. government for hemp products. THC mimics the action of anandamide, a neurotransmitter naturally produced in the human body, and binds to CB1 receptors in the endocannabinoid system found mostly in the brain. The extremely low levels of THC in hemp make hemp oil non-psychoactive and safe for all ages to use.
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
I had bilateral partial knee replacements 3-5 years ago then scar tissue removal in my right knee. I have always had some pain and stiffness in the right knee since my last surgery, probable due to more scar tissue. I am not ready for more surgery yet. I am mostly on my feet for 12 hours at work. About a year ago the pain in my knee got so intense I was only able to sleep for only several hours a night even with an ice bag on my knee. I started shopping for CBD online. Tried several brands before finding Lazarus which is much better than the others at a better price. My pain is 90-95 % gone and I sleep like baby all night. Helps with anxiety. Thank you! Please don’t stop making a great product.
Some companies, especially those who sell their products at a ridiculously low price, may use cheap methods when extracting CBD oil. This requires toxic solvents that are dangerous to our health such as propane, hexane, pentane and butane. Two of these are commonly used in gas stoves and ranges, such as propane and butane, and all of them are hydrocarbon gases found in petroleum.
We gave the highest points to companies that use a CBD distillate for their tinctures. The process of distillation creates an extract that is pure on a molecular level. There are people who think distillate is too pure, and that a full spectrum decarb produces a more effective tincture. But in light of the inconclusive evidence, we prefer a distillate. The process allows for a high degree of control as to the finished product. It’s also odorless and tasteless, so those tinctures tend to taste better.

I have fibromyalgia and piriformious syndrome (severe hip/leg pain) and for the past six months have been dealing with extreme pain and insomnia. Having exhausted all tricks, remedies, doctors, and medications without relief I decided to try Cbd oil. After only two days I have slept like a baby, had hours of continuous deep sleep, sleep app confirmed this. The Hip/leg pain is dulled, but dulled enough that I can do therapy stretches without screaming or crying. The nerve pain from fibro feels like it is asleep! It is the most amazing thing not to feel every nerve in your body after three years of constant pain. The cbd oil does give me a slight tummy ache after taking it but goes away in about an hour. And I do mean slight ache. So far no side effects or interactions. ( Will up date if do)
These drops are worth every penny! I first tried the 3,000 mg. Then bumped it up to 6000mg. I use about 1-1.5ml per day. I was hit head-on by a drunk when I was 19 in 1995. Coma 6 weeks hospital 6 months. This makes my life so much easier to live! Thank you Lazarus naturals for making such an awesome product!! And for making it so affordable! These products are worth their weight in gold!
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:

CBD Oil Full Spectrum

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