The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
While there is much debate on which form is better, this 2015 study (http://file.scirp.org/pdf/PP_2015021016351567.pdf) leans in favor of Full Spectrum products. There are many that believe that other cannabinoids, THC especially, are necessary to take full advantage of what cannabis has to offer. Ultimately, however, we are all different and it comes down to the individual user and their needs. If drug testing is a concern, you’re encouraged to seek out CBD isolate products (or terpsolates) instead of Full Spectrum.
Some people don’t mind, or even enjoy the natural taste of hemp oil tinctures. For those who are bothered by the distinctive herbal taste of hemp extract, a flavored CBD oil tincture may be better. We’ve selected a variety of both flavored and unflavored CBD oil tinctures in this roundup, and many of the brands selected offer multiple options. If you still can’t stand the flavor of CBD tincture, consider another option like CBD gummies or capsules. Topical CBD is another popular choice, especially if you’re treating body aches or certain skin problems.
And now, onto the thorny issue of legality. The simple answer to the question is yes – if it is extracted from hemp. The 2014 Farm Bill established guidelines for growing hemp in the U.S. legally. This so-called  “industrial hemp” refers to both hemp and hemp products which come from cannabis plants with less than 0.3 percent THC and are grown by a state-licensed farmer.
There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.
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There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:
Tetrahydrocannabinol, or THC, is one of the cannabinoids present in both marijuana and agricultural hemp, and it is the substance responsible for giving a psychoactive effect on the body. It is what gives a user a “high.” The reason why hemp is used over marijuana when creating CBD oil is because of the former’s innate low levels of THC over CBD, making it perfect for CBD oil processing.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.

There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
You may have read or heard in the news all the reports of people wanting to take CBD Oil for many ailments, some of which are cancer, epilepsy, chronic pain, TMJ, anxiety and diabetes.  And, many people are reporting some pretty fantastic improvements to their conditions after taking these oils.   The first thing most people want to know is: IS THERE ANY DIFFERENCE BETWEEN CANNABIDIOL FROM HEMP AND CANNABIDIOL FROM MARIJUANA?  And, the short answer is “no”; molecularly, CBD is CBD.  But, there are generally some differences in the CBD Extracts.  Let me explain this a bit further.
We take an extra step. Using advanced chromatography, Calm Hemp Oil is free of THC, while retaining the full spectrum of cannabinoids, terpenes and flavonoids that create an entourage effect and may support full-body health. Calm hemp oil comes from premium non-GMO strains of hemp, organically grown in Colorado, USA and is 100% natural, with a refreshing mint taste.
High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.
So not only do our products include a variety of phytocompounds, each with their own health benefits*, but all of these compounds work together, building on their individual strengths to further heighten the body's positive response to CBD. Scientists named this process the “entourage effect,” which means that our whole-plant hemp extract provides more complete health benefits than taking CBD on its own.
THC is the plant compound that makes a person feel ‘high’.  It is naturally found in much higher quantities in marijuana, and in virtually non-existent quantities in hemp. So, when taking a full spectrum cannabinoid extract from hemp, the THC level is so low that you do not feel ‘high’ or groggy.  But, when taking CBD extracted from marijuana, even the “low CBD” strains typically have enough THC to cause someone to feel slightly ‘high’ or at least sleepy or groggy.  And, if its NOT a low CBD strain of marijuana, then watch out, you will most likely experience a pretty significant ‘high’.

So, with all this talk of marijuana and THC and being ‘high’, we typically find the next question to be: IS CBD LEGAL.  And, as you are probably well aware, there are several states where CBD extracts from marijuana are legal, there are many more that are not.  But, point blank, CBD extracted from hemp, whether singularly or as a full spectrum cannabinoid blend, is legal in all 50 states.

High potency CBD tinctures are a great option for people who like a higher concentration of CBD. Each batch is third-party tested to ensure our product is natural, consistent and potent. For legal restrictions, we can’t make claims about specific health benefits of CBD. We recommend speaking to your doctor for more information about CBD’s benefits, and what serving size is right for you. For more information, visit our CBD Info & Knowledge Base page.

These studies conclude that “the higher efficiency of plant extract can be explained by additive or synergistic interactions between CBD, terpenes, and the minor phytocannabinoids or non-cannabinoids presented in the extracts. …because other phytocannabinoids, including Tetrahydrocannabivarin, Cannabigerol and Cannabichromene, as well as mono- and sesqui- terpenes, exert additional effects of therapeutic interest and the therapeutic synergy observed with plant extracts results in the requirement for a lower amount of active components, with consequent reduced adverse effects.”


The Virgin Hemp Seed Oil that holds the Full Spectrum Hemp CBD Oil together is rich in antioxidants and omega fatty acids, making it an invaluable supplement to any person’s daily diet. This makes the Full Spectrum one of the most nutritious and complete CBD oil products, perfect for those who seek to establish a balanced life through an equally balanced diet.
I am very pleased with the quality and the price of the high potency cbd. I have had my medical cannabis card for years and really became trusted with the high cost of my natural medicine, because the high costs and low cbd dosages found in the dispensaries. Now I can purchase high quality and high potency pure cbd oil at a great price without the worries of traveling with banned substances. Works better than xanax or antidepressants and no pharmaceutical side effects! I always take with my morning coffee and for pain and stress as needed. The only concern I have is with the shipping method as I would really benefit from USPS priority shipping instead of waiting for the long cross country ups ground, as the ups 3 day is very expensive. Besides the shipping options, I give this an A+! Thank you.
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.
In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.
In short, Cannabidiol – or CBD – is a cannabis compound that has many therapeutic benefits. Usually extracted from the leaves and flowers of hemp plants – though marijuana can also be a source – CBD oil is then incorporated into an array of marketable products. These products vary from the most common, like sublingual oils and topical lotions, to the less common (think CBD lattes). Basically, if you can dream it, you can buy it.
But there’s a big difference between the two. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things – it’s good for you, tastes great, and can be used in soap, paint – even as biodiesel fuel. However, hemp seed oil does not contain any concentration of cannabinoids at all, including CBD. So by all means, stock up at your local natural food store. Just don’t expect to reap the benefits of a true CBD oil when you cook with hemp seed oil.
This is a hugely beneficial effect of CBD. Free radicals are the culprits when it comes to oxidative damage and inflammation. But CBD’s antioxidant properties can help to combat the negative effects of everyday exposure to elements that increase the production of free radicals. These elements include pervasive, but hugely unsurprising, things like:
But there’s a big difference between the two. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things – it’s good for you, tastes great, and can be used in soap, paint – even as biodiesel fuel. However, hemp seed oil does not contain any concentration of cannabinoids at all, including CBD. So by all means, stock up at your local natural food store. Just don’t expect to reap the benefits of a true CBD oil when you cook with hemp seed oil.
I can’t assist with what you need, but I can tell you that I am a cancer survivor ( 15 years), with Chronic Fibro, arthritis and nerve damage . I was on prescribed pain meds for a long time. CBD has been a life saver. I have tried several of the above. For me, Bluebird is the best so far of them all. In terms of effectiveness , its heads and tails ( no pun intended) above the rest. They do have a program as well , yes. They are pricey . I also like Lazarus’s 25 mg Capsules as well.
Tetrahydrocannabinol is the most abundant cannabinoid in most medical and recreational marijuana strains. However, in hemp THC is a minor constituent and appears only in trace amounts under 0.3% by dry weight, as required by the U.S. government for hemp products. THC mimics the action of anandamide, a neurotransmitter naturally produced in the human body, and binds to CB1 receptors in the endocannabinoid system found mostly in the brain. The extremely low levels of THC in hemp make hemp oil non-psychoactive and safe for all ages to use.
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Full spectrum CBD also contains a variety of essential vitamins, minerals, fatty acids, protein, chlorophyll, terpenes, flavonoids, and fiber. When referring to CBD in the hemp plant, it’s important to understand that Hemp contains a large number of cannabinoids (in trace amounts), but the main compounds are CBD and cannabidiolic acid (CBDa). As CBDa is more abundant in the hemp plant, firms must decarboxylate the oil. This process heats the oil and changes CBDa into CBD.
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