While it is clear that full spectrum CBD may be more effective than isolate CBD, even at lower dosages, it may have some drawbacks. Full spectrum vs regular CBD comes down to this drawback for many people. If full spectrum CBD oil is not an option for you due to your obligations or lifestyle, this can help you make your decision more easily for sure.
It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.

All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.
Since our beginning, Medical Marijuana, Inc. has been striving to bring the health benefits of cannabinoids to the lives of as many people as possible through cannabinoid hemp oil supplements. With our knowledge of cannabinoids and the endocannabinoid system just scratching the surface of what’s possible, there is plenty of potential to find new uses for the myriad of cannabinoids available to us.
Received my first order about a month ago. Wanted to try it before giving feedback. I would frequently wake up at night with my hands just throbbing. I ordered the high potency tropical isolate. I have been taking a total of 60mg a day split into two doses. It has greatly reduced the pain in my hands, no longer waking up at night from the pain. I have also noticed it has a calming effect. Order was processed immediately and shipped right away with tracking. I am going to order the full spectrum when it is time for a refill as I can see it may work better for my needs. I would highly recommend LN and their products.
In addition, CBD oil can be extracted and manufactured through “supercritical CO2 extraction.” This process involves using carbon dioxide under high pressure in an extremely cold environment. Supercritical CO2 extraction requires expensive equipment, more complex refinement process and production expertise, but it ensures that CBD oil maintains its purity all through the process.
I have also called a couple places to get some input about what we may need, but they all said they cannot give advice. Then HOW do we know what to get. As for MOST of us, we are by no means well off. Quite the opposite, in fact. So to keep “trying” a bunch of different ones is not an option. Blue Bird in CO give discounts to low income, so would like to use their products if possible.
This is my experience with taking CBD 3000mg for the last 6 months. My blood pressure has gone down, I am able to sleep better, the eczema on my hand has disappeared (using a drop or two twice a day on the area). Sort of did an assessment of my body/joints. Everything feels different in a good way. Joints seem to move smoother than before taking CBD. All is great here. Thanks, Lazarus Naturals for such great reasonably priced products.
To better understand how these two CBD formulas differ, imagine being presented with two types of spaghetti sauce. In the first bowl, you’ll find a simple spaghetti sauce made out of pure tomatoes (CBD isolate). In the second bowl, you can find a more complex spaghetti sauce, containing roasted garlic and fragrant Italian herbs (full spectrum CBD). It’s clear that both bowls are holding spaghetti sauce – but the second recipe is more flavorful and interacts with one’s taste buds differently (also known as the “entourage effect”).
CBD is extracted from both plants in just the same way.  But, when it’s extracted from hemp, it is often times, extracted by itself.  Beyond CBD, there are a host of other plant compounds, called cannabinoids, present in both plants, including THC (more on THC later).  We won’t go into all the other compounds in this article as that would take a book to detail, but a short list of the most common ones are:  CBDA, CBG, CBGA, CBN, Terpenes and Phytonutrients, and THC.  Generally, when CBD is extracted from marijuana, all these compounds are extracted together and the extract is then formulated into various products, thus giving the user this “full spectrum” of cannabinoids.  Generally, when CBD is extracted from hemp, it may or may not include this full spectrum of cannabinoids.  So, this is the first important distinction between CBD from hemp and CBD from marijuana.  When it comes from hemp, it may or may not include all the other cannabinoids.  When it comes from marijuana, it almost always does, including the cannabinoid: THC.  (Note:  ALL Highland Pharms products use a full spectrum of cannabinoid extract.)
Cannabinol results from the degradation of THC. There is little of it in the fresh plant, but decarboxylation often raises the amount of CBN in the plant as an effect. CBN is only mildly psychoactive and has a higher affinity for the CB2 receptor than the CB1 receptor, linking CBN to the body’s immune system. In hemp oil, CBN is present in levels of 0.2% or lower.
As the term suggests, full spectrum CBD comes with all the of the cannabinoids present in the plant. In hemp oil, this includes a long list of cannabis compounds, such as Cannabinol (CBN), Cannabicyclol (CBL), Tetrahydrocannabivarin (THCV) and Cannabichromevarinic Acid (CBCVA). It is crucial to point out that small amounts of THC can also be found in hemp. The government regulates concentration levels at 0.3 percent (dry weight) for “industrial hemp” products, resulting in very limited cerebral stimulation.
Full Spectrum generally refers to CBD oil products that not only contain CBD,but also contain some terpenes and other cannabinoids such as CBG, CBN and even some THC. Usually these will be in ratios that were naturally occurring and extracted from the plant and specific strain. But they are also occasionally added back into products as an isolated form to raise the potency of the product. For those that get drug tested, Full Spectrum is something to be cautious about. The THC found in full spectrum hemp products is minimal (less than 0.3%), but can still trigger positive drug tests.
I can’t say enough good things about LN CBD tinctures. The 750mg high potency is a wonderful tasting full spectrum tincture that helps me with back pain, ***** and overall restlessness. I’m so thankful I found LN. I’ve compared the prices of all the truly legitimate CBD sellers (via r/CBD reddit group) and you get the best product per your dollar when you buy LN.

The Virgin Hemp Seed Oil that holds the Full Spectrum Hemp CBD Oil together is rich in antioxidants and omega fatty acids, making it an invaluable supplement to any person’s daily diet. This makes the Full Spectrum one of the most nutritious and complete CBD oil products, perfect for those who seek to establish a balanced life through an equally balanced diet.


Although low, the original amount of THC present in hemp may still cause a certain level of psychoactive effects when processed incorrectly. Remember, CBD oil is made from the extracts of hundreds, even thousands, of hemp plants, therefore, no matter how small a percentage of THC there is in hemp, it may still have a high concentration on CBD oils that have been processed poorly, especially since the equipment needed to properly process CBD oil from hemp can be costly.
All I am seeing on this site is this brand is fantastic and that brand is fantastic! I don’t think I could trust any of these with the exception of one. I believe the only way to actually get good quality CBD is from a state licensed dispensary. Everyone else just wants to make a quick buck by jumping on the hype that it is now legal in all 50 states! I have cancer and herniated discs and fibromyalgia, asthma, PTSD, CFS severe anxiety, etc and will be starting radiation shortly. My pain right now is off the charts. I am afraid of most medications and pretty much will not take too many things. So when I get the CBD oil I will do it in front of a doctor to make sure of allergies. It will have to be of high quality and something that will not get me high! The fear of taking something from just any online distributor doesn’t ensure quality. If anyone out there can tell me with the most positive knowledge that a product is what it is then you can let me know. Any recommendations?
When seeking out Full Spectrum products, you may come across some called “Broad Spectrum” that claim to have 0% THC. It’s important to verify lab tests on these products to make sure that this is not a false claim and you’re encouraged to still exercise caution with these products if drug testing is a concern. These products have sometimes gone through additional processing to try to isolate and remove as much THC as possible while still maintaining some of the other cannabinoids and terpenes.
As each Full Spectrum Hemp CBD Oil bottle comes with a precise dropper, it’s easy to exactly measure your serving size and adjust it according to your body’s needs. This also allows you to easily combine the Full Spectrum with any other CBD product to introduce more variety and enrich your daily CBD pleasure. You can try the Full Spectrum Hemp CBD Oil alongside any CBD edible or right before your CBD vape for a synergistic effect.
THC is the plant compound that makes a person feel ‘high’.  It is naturally found in much higher quantities in marijuana, and in virtually non-existent quantities in hemp. So, when taking a full spectrum cannabinoid extract from hemp, the THC level is so low that you do not feel ‘high’ or groggy.  But, when taking CBD extracted from marijuana, even the “low CBD” strains typically have enough THC to cause someone to feel slightly ‘high’ or at least sleepy or groggy.  And, if its NOT a low CBD strain of marijuana, then watch out, you will most likely experience a pretty significant ‘high’.
For our review of the best CBD topicals available online, we focused only on companies which make third-party, independent lab results available to consumers. Lab results are available online, included in the order, or on request. It’s vitally important that consumers know exactly what products they’re consuming: how strong it is, and whether it has any impurities. We also focused on brands with fast, friendly customer service and easy to use websites.
Let’s not forget about terepenes and flavonoids too. While not cannabinoids from hemp, they are compounds found in hemp and other plants. Terpenes are fragrant oils that bind to receptors in the human body and carry a variety of health benefits.* Flavonoids are a group of phytonutrients that serve as cell messengers with their own health-promoting benefits,  
In the U.S., we live in a culture where more is often perceived as being better.  And it’s easy, without even thinking about it, to apply that approach to CBD dosing. But when it comes to CBD, more is not necessarily better. In fact, for many, less CBD is more effective. One way to determine your optimal dosage is to start with a small amount of CBD for a couple weeks and then slowly increase your dosage, carefully taking note of symptoms, until you’re seeing the results you want.
CBD (cannabidol) is gaining popularity as a hot term in the health and wellness world —and will continue to do so as more people come to understand how beneficial* it can be to the human body.  But CBD isn’t the only phytocompound we’re excited about in our Charlotte’s Web hemp extract. That’s because our extract is more than just CBD.  Among the beneficial* compounds that come from plants, we have more than 80 of them. 

This is my 3rd time ordering. I’m still happy with this company. People are loving my tinctures and my balm I can hardly keep on the shelf. I have had a handful of customers ask me for a tincture without coconut oil though due to allergies. They don’t offer this in a tincture only in Isolate which I’m still not sure if it will work the same. So I’m hoping a coconut free version will be available sometime in the future.
The label of this CBD oil tincture was not as easy to read as other products. Palmetto Harmony’s hemp is grown in Kentucky. This family operated business began when CBD offered unique benefits to their ailing child, Harmony. In addition tinctures, they offer topicals, capsules, pet products and even transdermal CBD patches. This tincture was selected by our friends at Anavii Market.

Our high potency CBD tinctures are carefully extracted and formulated in-house to bring you a high-quality product at a price anyone can afford. Our high potency tinctures are over three times as potent as our Standard Potency CBD tinctures. This product is available in a 15ml bottle containing 750mg, a 60ml bottle containing 3,000mg, or a 120ml bottle containing 6,000mg. We use graduated droppers, so you can easily see how much tincture you are taking. Each ml contains 50mg of CBD. Our high potency CBD tinctures contain our whole plant CBD extract, which feature a spectrum of naturally occurring cannabinoids and terpenes. Our CBD extract is blended with hemp seed oil, fractionated coconut oil, and avocado oil.
Cannabigerol is known as the stem cell cannabinoid for its role as a precursor to other cannabinoids found in hemp and marijuana. Previously overlooked as a significant cannabinoid, the role of CBG is becoming better understood, and companies like Medical Marijuana, Inc.’s AXIM® Biotechnologies are starting to research its potential. Because most CBG is transformed into other cannabinoids like CBD or THC by the cannabis plant, natural CBG levels are low in most processed cannabis plants.
CBD is found bonded naturally to fats in many organic sources, most notably within a human mother’s breast milk.  This allows the P-450 enzyme in the liver to naturally break down CBD to then utilize it within the endocannabinoid system.  We replicate this process, in the most organic way we can, through bonding the hemp-derived cannabinoids in MCT Coconut oil.  We want your experience using our hemp oil to be easy and accurate!

There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.
Isolate is typically the CBD oil product of choice for those who get drug tested or are sensitive to other cannabinoids such as THC. Products labeled as Isolate will generally be highlighted as being 99+% pure CBD. Usually, these products will have nothing but CBD in them because the CBD has literally been isolated from everything else. You can find pre-made isolate oils that typically consist of a carrier oil, such as MCT Oil, infused with the crystalline isolate powder. You can also find the “raw” crystalline powder or slabs (a form of concentrate) on its own.

When CBD is referred to as full spectrum or whole plant CBD, it means that the CBD contains all other cannabinoids found in the marijuana plant including CBN (Cannabinol), CBG (Cannabigerol), and THCV (Tetrahydrocannabivarin), to name a few. And yes, along with these cannabinoids, Full Spectrum CBD also contains trace amounts of THC (Tetrahydrocannabinol), but in very low concentrations (up to .3%), resulting in very minimal psychoactive stimulation.
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