While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
Another field in which CBD is creating a buzz is in the area of mood disorders like anxiety and depression. Both conditions have been treated with a variety of medications, courtesy of Big Pharma, that have had varying levels of success. Again, the long list of side effects can be off-putting to someone who just wants to get through the day without the sweaty tension of anxiety or the gray haze of depression.
Thank you for a great product. I have been in constant pain for almost 17 years. It has helped relax my muscles so much better than what I can get prescribed by my doctors here. I am using Tylenol intermittently with it to space out the dosage. I haven’t noticed any side effects from it . This is my first time trying this and I am well pleased. Thank you again for this, it is a game changer for me.

After starting with another 300 mg isolate from another brand, I ordered a 225 regular tincture LN. While some like the full spectrum flavor, I can’t handle putting it under my tonge (the most efficient way to absorb it as opposed to swallowing it, ingesting it, which takes a higher dose for the same effect). I ordered the wintermint 750 high potency which has really helped me with back pain from an injured disc, and arthritis in my hip. I’m not pain free, but it is dramatically better. And I can put it under my tongue. I would like to take a full spectrum high potency that tastes like the isolate. How about it, guys? Please. Could you email me?
Hi Diane, we wanted to give some feedback on this subject. Our products are made from hemp which is naturally low in THC, however, they do contain federally acceptable levels of THC. Our full spectrum products contain up to 0.3% THC by weight. Our isolate based tinctures have an undetectable level of THC per our testing standards. However, we do not recommend CBD products for those who are worried about drug testing as there are many shared compounds between hemp and marijuana that could cause a false positive.
Not to be confused with its botanical cousin marijuana, premium hemp oil is extracted from the hemp plant. While hemp and marijuana share many of the same beneficial compounds—cannabinoids, terpenes, and antioxidant flavonoids—there is one important difference. Hemp has only trace amounts of THC, the psychoactive compound found in high amounts in marijuana, so there is no “high” when taking full spectrum hemp oil, just health benefits.
There are new CBD companies coming online every week – these span the range from truly awful to really great. So how to choose the best? The quality of the CBD oil itself is obviously the most important factor – and many companies do take the quality of their products seriously. To reward those companies, we gave more weight to the quality of the product than any other category.
There’s also been a lot of talk lately about “microdosing” CBD. This refers to an incremental process of finding your minimum effective dose. You can do this with any concentration of CBD oil, but lower concentrations will take longer. In a 2017 article in Rolling Stone, Dr. Dustan Sulak outlines his protocol for microdosing. You can begin this process by asking yourself three questions:

Mimi says the effective oils are made from the marijuana plant, not hemp. Why are you rating only hemp oils? Are hemp oils the only oils that do not have any THC? The other question that arises is the difference between ml and mg in measuring the strength of these oils. They are quoted as ml, but there is the question of the “density” limit of 95mg? Very confusing.

This is my experience with taking CBD 3000mg for the last 6 months. My blood pressure has gone down, I am able to sleep better, the eczema on my hand has disappeared (using a drop or two twice a day on the area). Sort of did an assessment of my body/joints. Everything feels different in a good way. Joints seem to move smoother than before taking CBD. All is great here. Thanks, Lazarus Naturals for such great reasonably priced products.


So a full spectrum decarb got higher points than isolate (“decarb” just refers to the process of decarboxylation which turns raw CBD into activated CBD). We also gave more points to companies with a “broad spectrum” tincture. Broad spectrum CBD oil includes a range of other cannabinoids, but minus the THC – which is generally what people using isolates are trying to avoid.

The manufacturer will probably give you a recommended dosage, but bear in mind that this isn’t set in stone. What you need to find is your own minimum effective dose. “Minimum effective dose” is a medical term which refers to the amount of a substance you need for the results you want, and above which, the substance doesn’t increase in effectiveness.
There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.
There is a lot of confusion out there. Both industrial hemp & marijuana are separate strains of the cannabis plant (hemp is c. sativa and marijuana can be either other strains of c. sativa or c. indica–marijuana has much, much more THC than hemp, which has little-to-none). The site is reviewing only CBD oils made from industrial hemp (more expensive from flower, cheaper & weaker from seeds & stalks) because those are the only kinds of CBD oil one can buy in all 50 states anywhere (not just licensed dispensaries), whether the state allows recreational weed, medical marijuana with an official cannabis ID card, or no marijuana whatsoever for any purpose.

After starting with another 300 mg isolate from another brand, I ordered a 225 regular tincture LN. While some like the full spectrum flavor, I can’t handle putting it under my tonge (the most efficient way to absorb it as opposed to swallowing it, ingesting it, which takes a higher dose for the same effect). I ordered the wintermint 750 high potency which has really helped me with back pain from an injured disc, and arthritis in my hip. I’m not pain free, but it is dramatically better. And I can put it under my tongue. I would like to take a full spectrum high potency that tastes like the isolate. How about it, guys? Please. Could you email me?

In fact, numerous studies have looked at the relationship between CBD and pain, and the results are promising. Researchers have looked at various kinds of pain – from joint pain to cancer pain. One finding is that CBD increases levels of glutamate and serotonin – both neurotransmitters that play a role in pain regulation. And CBD’s anti-inflammatory properties help by tackling the root cause of much chronic pain.
Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity. But THC metabolites are stored in the fat cells of your body, building up over time. If you ever need to take a drug test, this could create an issue for you.
As shown in the chart above, each cannabinoid offers different benefits for a wide variety of ailments. Notably, CBD offers most of the benefits of each cannabinoid combined. While there is no debate that CBD offers the most benefits compared to any single cannabinoid, many wonder if CBD alone is more effective for treating ailments than all the cannabinoids combined.
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