The aforementioned entourage effect is the main reason behind the efficacy of whole plant extracts. There are over 100 ‘identified’ compounds in the cannabis plant. While most of these compounds have their own therapeutic benefit, they combine synergistically to provide a far better performance than any single compound, including CBD. Here are a couple of examples of conditions that benefit from the entourage effect:
CBD Oil Full Spectrum
Strength is also an extremely important consideration. Beginners may find that it’s easier to control dosage using a lower strength tincture. On the other hand, experienced CBD consumers know that high strength tinctures are more cost effective. Although stronger tinctures cost more, you get more CBD oil and other beneficial cannabinoids in each drop. Most CBD brands offer more than one option for strength.
Finally, in general, we almost always recommend full spectrum tinctures over supplements made from isolates (extracts of CBD alone). Full-spectrum or whole plant tinctures take advantage of the ‘entourage effect’ that comes from combining all the naturally occurring chemicals found in the hemp plant. Isolates are great for cooking with CBD or consumers that are especially sensitive to the taste of hemp extract, but some research suggests they may be less effective for certain uses than full spectrum extracts. All but two of the brands below are made from full spectrum hemp, and the exceptions are clearly noted.
I purchased Ananda professional full spectrum Extract 600 20/mg/ml CBD oil. I started with .5ml dose the first night right before bedtime. I did not sleep well. I tried the same dose the following evening, and again, poor sleep. I tried it for two more nights and had the same results. I’m very sensitive to steroids and will only use them as a last resort, but the way I felt after taking the CBD oil, reminded me of how poor my sleep is on steroids. Or how vitamin B12 can affect me if I take it too late in the day. I have a lot of inflammation and pain and hoped the CBD oil would help. I am quite surprised at my reaction to it. Anyone else have trouble sleeping when taking it?
I had bilateral partial knee replacements 3-5 years ago then scar tissue removal in my right knee. I have always had some pain and stiffness in the right knee since my last surgery, probable due to more scar tissue. I am not ready for more surgery yet. I am mostly on my feet for 12 hours at work. About a year ago the pain in my knee got so intense I was only able to sleep for only several hours a night even with an ice bag on my knee. I started shopping for CBD online. Tried several brands before finding Lazarus which is much better than the others at a better price. My pain is 90-95 % gone and I sleep like baby all night. Helps with anxiety. Thank you! Please don’t stop making a great product.
While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
THC is the plant compound that makes a person feel ‘high’. It is naturally found in much higher quantities in marijuana, and in virtually non-existent quantities in hemp. So, when taking a full spectrum cannabinoid extract from hemp, the THC level is so low that you do not feel ‘high’ or groggy. But, when taking CBD extracted from marijuana, even the “low CBD” strains typically have enough THC to cause someone to feel slightly ‘high’ or at least sleepy or groggy. And, if its NOT a low CBD strain of marijuana, then watch out, you will most likely experience a pretty significant ‘high’.
It was previously believed that CBD in its isolated form was more potent and concentrated than full spectrum CBD; however, in 2015, the theory was debunked by a study from the Lautenberg Center for General Tumor Immunology in Jerusalem. In the study, researchers administered full spectrum CBD and CBD isolate to two different groups of mice. When comparing the data of the two groups, the results proved that the group administered with full spectrum CBD were provided with higher levels of relief. Furthermore, the study demonstrated that full spectrum CBD continued to provide relief as the dose increased, while CBD Isolate did not provide the same effect when there was an increase in dosage.
Essential fatty acids are necessary for maintaining heart and cardiovascular health. The two primary essential fatty acids — Omega 3 and Omega 6 — are ideally consumed at a ratio of around 3:1. Unfortunately, in the typical American diet, that ratio is close to 25:1. Full-spectrum hemp oil offers the two essential fatty acids in the optimal 3:1 ratio.
I was highly impressed with this product, and honestly surprised. I have tried many different cbd products, from many different companies, only to find them to be mediocre at best. Lazarus naturals, by far has the most effective cbd I’ve yet to try. With only a 1ml serving, I was able to nullify my knee and foot pain after a 10 hour shift of non-stop standing and walking. Will for sure be a returning customer.